The experience of clinical use of the new Russian myorelaxant of the non-depolarizing action vero-pipecuronium (pipecuronium bromided) manufactured by "Veropharm" is described. Vero-pipecuronium was found to ensure splendid and good conditions for the intubation of the trachea and to maintain reliably myorelaxation. The recommended doses and availability of an antidote (prozerine) provide for a sufficiently controllable myorelaxation. Vero-pipecuronium does not virtually exert any effect on the parameters of hemodynamics and can be successfully used in patients with a high anesthetic risk including heart surgeries. Thus, Russian vero-pipecuronium has now an effective and safe myorelaxant manufactured inside the country, whose parameters are not inferior to those of pipecuronium bromide (arduan) manufactured by "Gedeon Richter", Hungary. Since the described drug is made in Russia, one can hope it will be highly effective both economically and pharmacologically.
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Biochem Pharmacol
December 2023
Eppley Institute, University of Nebraska Medical Center, Omaha NE, USA.
Butyrylcholinesterase (BChE) is present in plasma and numerous cells and organs. Its physiological function(s) is(are) still unclear. However, this enzyme is of pharmacological and toxicological importance.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
October 2020
Clinical Hospital of St. Luka, St-Petersburg, Russia.
Objective: To improve the algorithm of differential diagnosis and complex treatment of patients with CR.
Material And Methods: Forty-two patients with CR were divided into 2 groups. Patients of the first group (=21) received basic treatment (NSAID, myorelaxants, local injections with glucocorticoids (on demand), B vitamins and non-pharmacological methods) and the anticholinesterase drug ipidacrine.
Zh Nevrol Psikhiatr Im S S Korsakova
July 2020
Volgograd State Medical University, Volgograd, Russia.
Unlabelled: Chronic nonspecific pelvic pain is one of the most pressing problems of modern neurology, due to complex interdisciplinary diagnostic and therapeutic studies. The etiology and pathophysiology of pain syndromes are studied from the point of view of each individual medical specialty, but do not consider the relationship and interaction of pathogenetic factors. In many areas, clinical guidelines for the treatment of chronic pelvic pain have been developed, but without taking into account the multidisciplinary approach to this polyetiological disease.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
December 2019
Kazan State Medical University, Kazan, Russia.
Despite the variety of treatment options, pain syndromes are widespread in the population. Adjuvant methods, in particular vitamins and vitamin combinations, are widely used, along with nonsteroidal anti-inflammatory drugs, myorelaxants and anticonvulsants, by physicians of different specialties. In recent years, new drugs containing pyrimidine nucleotides (uridine monophosphate) were brought to market.
View Article and Find Full Text PDFVestn Otorinolaringol
January 2020
Federal State Autonomous Institution 'National Medical Research Center Of Children's Health' Of Ministry Of Healthcare Of Russia, Moscow, Russia, 119991.
In this article, we consider the influence of combined general anesthesia on the results of electrically-involved stapedial reflex threshold (esrt) registration. We pay a special attention to the anesthesia to exclude its influence on the esrt. This study included 52 patients with bilateral chronic neurosensory hearing impairment.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!