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The electronic health record as an interactional and epistemic resource: Insights from pediatric well-child visits.
Patient Educ Couns
January 2025
Department of Education Studies, University of Bologna, Via Filippo Re 6, Bologna, 40126, Italy. Electronic address:
Objective: Electronic health records (EHRs) have increasingly become integral to contemporary medical consultations, including pediatric care. This study aims at exploring the interactional use of the EHR during naturally occurring pediatric well-child visits, focusing specifically on how pediatricians and parents manage knowledge concerning infants' growth inscribed in the EHR.
Methods: Conversation analysis is used to analyze 23 video-recorded Italian well-child visits involving two pediatricians and twenty-two families with children aged 0-18 months.
Understanding the Myelin Ratio from First Principles, Its Derivation, Uses and Artifacts.
ASN Neuro
January 2025
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, USA.
In light of the increasing importance for measuring myelin ratios - the ratio of axon-to-fiber (axon + myelin) diameters in myelin internodes - to understand normal physiology, disease states, repair mechanisms and myelin plasticity, there is urgent need to minimize processing and statistical artifacts in current methodologies. Many contemporary studies fall prey to a variety of artifacts, reducing study outcome robustness and slowing development of novel therapeutics. Underlying causes stem from a lack of understanding of the myelin ratio, which has persisted more than a century.
View Article and Find Full Text PDFChanges in urinary concentrations of contemporary and emerging chemicals in commerce during the COVID-19 pandemic: Insights from the Environmental influences on Child Health Outcomes (ECHO) program.
PLoS One
January 2025
Department of Environmental Health Sciences, Columbia University, New York, NY, United States of America.
Previous research indicates that the COVID-19 pandemic catalyzed alterations in behaviors that may impact exposures to environmental endocrine-disrupting chemicals. This includes changes in the use of chemicals found in consumer products, food packaging, and exposure to air pollutants. Within the Environmental influences on Child Health Outcomes (ECHO) program, a national consortium initiated to understand the effects of environmental exposures on child health and development, our objective was to assess whether urinary concentrations of a wide range of potential endocrine-disrupting chemicals varied before and during the pandemic.
View Article and Find Full Text PDFValue of routine blood count surveillance in detecting relapse in acute lymphoblastic leukemia.
Front Pediatr
January 2025
Department of Pediatric Oncology, King Abdullah Specialized Children's Hospital, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia.
Background: Children with acute lymphoblastic leukemia (ALL) have excellent outcomes, with >85% survival without relapse following contemporary therapies. Clinical and complete blood count (CBC) assessments are commonly used surveillance methods to detect relapses. We aimed to evaluate the efficacy of routine blood testing for detecting relapse using a systematic method of assessing normal and abnormal results.
View Article and Find Full Text PDFInterventions for adult congenital heart disease.
Nat Rev Cardiol
January 2025
Quebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
Advances in imaging diagnostics, surgical techniques and transcatheter interventions for paediatric patients with severe congenital heart disease (CHD) have substantially reduced mortality, thereby extending the lifespan of these individuals and increasing the number of adults with complex CHD. Transcatheter interventions have emerged as an alternative to traditional open-heart surgery to mitigate congenital defects. The evolution of techniques, the introduction of new devices and the growing experience of operators have enabled the treatment of patients with progressively more complex conditions.
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