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Effectiveness of rotavirus vaccine following introduction in the childhood immunization program in Northeast India.
Indian J Med Microbiol
January 2025
Department of Microbiology, RIMS, Lamphelpat, Imphal - 795004, Manipur, India. Electronic address:
Background: Rotavirus diarrhoea is a major cause of mortality and morbidity in children under five years of age. The WHO has recommended vaccination against this agent especially in countries with high mortality rates. As India accounts for almost a quarter of worldwide rotaviral diarrhoea cases, the government has introduced indigenously manufactured vaccines in the national immunization schedule which has been implemented in four phases.
View Article and Find Full Text PDFXanomeline-Trospium for Adults with Schizophrenia Experiencing Acute Psychosis: A Systematic Review and Meta-analysis of Safety and Tolerability Outcomes.
Pharmacopsychiatry
January 2025
Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
The United States Food and Drug Administration approved the xanomeline-trospium combination in September 2024 for treating schizophrenia, based in part on three double-blind, randomized placebo-controlled trials in adults with schizophrenia experiencing acute psychosis. This random-effects model pairwise meta-analysis of those three trials found that xanomeline-trospium was comparable to placebo in terms of all-cause discontinuation, discontinuation rate due to adverse events, Simpson-Angus Scale score change, Barnes Akathisia Rating Scale score change, body weight change, body mass index change, blood pressure change, serum total cholesterol change, blood glucose change, QTc interval changes, and the incidence of headache, somnolence, insomnia, dizziness, akathisia, agitation, tachycardia, gastroesophageal reflux disease, diarrhea, increased weight, and decreased appetite. However, xanomeline-trospium was associated with a higher incidence of at least one adverse event, dry mouth, hypertension, nausea, vomiting, dyspepsia, and constipation, and increased serum triglyceride compared with placebo.
View Article and Find Full Text PDF[Investigation of Virulence Genes in Campylobacter Species Isolated from Patients with Acute Diarrhea].
Mikrobiyol Bul
January 2025
Selçuk Üniversitesi Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Konya.
Akut gastroenterit dünya genelinde en yaygın enfeksiyon hastalıklarından biridir. Bu hastalıklar gelişmekte olan ülkelerde çocuk ölümlerine ve ciddi ekonomik kayıplara neden olmuştur. Hastalık genellikle yaygın diyare şeklinde kendini gösterse de bazı olgularda şiddetli enfeksiyon belirtilerine, hatta ölümlere neden olmuştur.
View Article and Find Full Text PDFBeyond the Atypical: Gastrointestinal Manifestations in Kawasaki Disease.
Cureus
December 2024
General Pediatrics, Al Qassimi Women's and Children's Hospital, Sharjah, ARE.
Kawasaki disease (KD) is an acute vasculitis mainly seen in children, with a specific risk for coronary artery involvement. Atypical symptoms can sometimes result in missed diagnoses, delaying necessary treatment and increasing the chances of serious cardiovascular complications. We report a case of a six-month-old previously healthy girl who had not been vaccinated.
View Article and Find Full Text PDFAlive in biliary fluid in patient: A case report.
World J Gastroenterol
January 2025
Department of Gastroenterology, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen 518000, Guangdong Province, China.
Background: (), is a prevalent parasitic worm that infects humans. It is found all over the world, particularly in tropical and subtropical areas. Strongyloidiasis is caused mostly by the parasitic nematode .
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