We report on a stand-alone single-chip (7 x 10 mm) atomic force microscopy unit including a fully integrated array of cantilevers, each of which has an individual actuation, detection, and control unit so that standard atomic force microscopy operations can be performed by means of the chip only without any external controller. The system offers drastically reduced overall size and costs as well as increased scanning speed and can be fabricated with standard complementary metal oxide semiconductor technology with some subsequent micromachining steps to form the cantilevers. Full integration of microelectronic and micromechanical components on the same chip allows for the controlling and monitoring of all system functions. The on-chip circuitry, which includes analog signal amplification and filtering stages with offset compensation, analog-to-digital converters, a powerful digital signal processor, and an on-chip digital interface for data transmission, notably improves the overall system performance. The microsystem characterization evidenced a vertical resolution of < 1 nm and a force resolution of < 1 nN as shown in the measurement results. The monolithic system represents a paradigm of a mechatronic microsystem that allows for precise and fully controlled mechanical manipulation in the nanoworld.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC535376 | PMC |
http://dx.doi.org/10.1073/pnas.0405725101 | DOI Listing |
Anal Methods
January 2025
Microelectronic Research & Development Center, School of Mechatronics Engineering and Automation, Shanghai University, Shanghai 200444, China.
An integrated magnetoimpedance (MI) biosensor microfluidic magnetic platform was proposed for the evaluation of the cardiac marker, cardiac troponin I (cTnI). This bioanalyte evaluation platform mainly comprised three external permanent magnets (PMs), one MI element, two peelable SiO film units and a microfluidic chip (MFC). The MI element was made of micro-electro-mechanical system (MEMS)-based multilayered [Ti (6 nm)/FeNi (100 nm)]/Cu (400 nm)/[Ti (6 nm)/FeNi (100 nm)] thin films and designed as meander structures with closed magnetic flux.
View Article and Find Full Text PDFTalanta
December 2024
Engineering Research Center of Smart Microsensors and Microsystems, Ministry of Education, College of Electronics and Information, Hangzhou Dianzi University, Hangzhou, Zhejiang, 310018, China; China-Israel Polypeptide Device and Application Technology Joint Research Center, Hangzhou, 310027, China. Electronic address:
Nitrogen dioxide (NO) is an important contaminant that poses a severe threat to environmental sustainability. Traditional inorganic NO gas detectors are generally used under harsh operating conditions and employ environmentally unfriendly resources, thus preventing widespread practical applications. Herein, self-assembled peptide microtubes (SPMTs) are combined with SnO nanoparticles (NPs) to develop a bioinspired NO gas sensor.
View Article and Find Full Text PDFAdv Mater
November 2024
Institute of Advanced Battery Materials and Devices, College of Materials Science and Engineering, Beijing University of Technology, Beijing, 100124, P. R. China.
Elemental doping is widely used to improve the performance of cathode materials in lithium-ion batteries. However, macroscopic/statistical investigation on how doping sites are distributed in the material lattice, despite being a key prerequisite for understanding and manipulating the doping effect, has not been effectively established. Herein, to solve this predicament, a universal strategy is proposed to quantitatively identify the locations of Al and Mg dopants in lithium-rich layered oxides (LLOs).
View Article and Find Full Text PDFNat Commun
September 2024
State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, PR China.
Adv Mater
September 2024
Department of Mechanical and Mechatronics Engineering, Waterloo Institute for Nanotechnology, Materials Interface Foundry, University of Waterloo, Waterloo, N2L 3G1, Canada.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!