In two patients, a girl aged 2 and a man aged 52 years, who had suffered a severe crush trauma, acute compartment syndrome of the foot was diagnosed. Decompression by means of one medial and two dorsal dermato-fasciotomy incisions was carried out and fractures of the metatarsals were repaired using K-wires. The girl recovered completely, but the man developed progressive necrosis in the flexors of the foot and on the skin on the foot sole which necessitated amputation of the foot. Acute compartment syndrome of the foot is an uncommon disease and is mainly characterised by extreme pain and often diffuse swelling of the foot. It is a serious threat to the foot which can lead to severe long-term complications including contractures, deformity and paralysis. Compartment syndrome of the foot is a primary clinical diagnosis. When in doubt, direct pressure measurement of the foot compartments should be done by means of needle catheterisation. If compartment pressure exceeds 30 mm Hg, acute dermato-fasciotomy of all nine compartments is indicated. A combined medial and dorsal approach is adopted to release the foot compartments; three incisions are usually sufficient. If fractures are present, these are repaired at the same time. Within four hours an unnoticed compartment syndrome can lead to irreversible ischaemia of the nerves and muscle tissue with long-term irreversible consequences.
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Int Immunopharmacol
January 2025
Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, University of Eastern Piedmont 28100 Novara, Italy; Center for Translational Research on Autoimmune and Allergic Diseases, University of Eastern Piedmont 28100 Novara, Italy. Electronic address:
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to widespread post-acute sequelae of COVID-19 (PASC), affecting multiple body systems. Despite its prevalence, PASC's pathogenesis remains unclear, with hypotheses suggesting viral persistence, immune activation, and autoimmune responses among the pathogenetic mechanism. This study aimed to evaluate T cell memory response in PASC patients, one year post-hospital discharge and correlate it with clinical parameters to identify a potential PASC-associated fingerprint.
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January 2025
Department of Vascular Surgery, Royal Perth Hospital, Perth 6000, Australia; University of Western Australia, School of Surgery, Perth 6000, Australia. Electronic address:
Introduction: We present a unique case of acute aortic occlusion secondary to infective endocarditis (IE).
Presentation Of Case: An Aboriginal Australian woman with systemic lupus erythematosus presented with fever, confusion, tachycardia, and tachypnoea and had cold, pulseless, insensate, and paralysed lower limbs. Computed tomography angiography revealed multifocal occlusion of the distal aorta and lower limb vessels.
Int J Surg Case Rep
January 2025
School of postgraduate, Amoud University, Somalia; Faculty of Science, Charles University, Czechia. Electronic address:
Introduction: Giant inguinoscrotal hernias (GIH), defined as hernias extending below the inner thigh midpoint in a standing position, are rare and often seen in resource-limited settings due to delayed medical care. These hernias pose surgical challenges, particularly in low- and middle-income countries (LMICs), where standardized management protocols are lacking, and risks such as cardiorespiratory compromise are significant.
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JSES Rev Rep Tech
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Department of Orthopaedic Surgery and Sports Medicine, University at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, USA.
J Am Podiatr Med Assoc
January 2025
*Western University of Health Sciences, College of Podiatric Medicine, Pomona, CA.
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