Thrombocytopenia is a blood dyscrasia common in AIDS patients that may result from increased viral load and diminished CD4 T lymphocytes. We evaluated the rate of thrombocytopenia (platelet count < 100 000/microL) in 170 HIV-infected patients (161 males and 9 females) from May 2000-April 2001 in Kermanshah, Islamic Republic of Iran. All except 7 females were injecting drug users. While 34 patients had thrombocytopenia, 3 had severe thrombocytopenia (platelet count < 20 000/microL). Although prevalence was similar in various stages of HIV infection (18.5%-22.5%), severe thrombocytopenia was in patients with CD4 T cell count < 200 cells/microL. There were no other associated conditions. Mild thrombocytopenia is common in HIV-infected patients in our region.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Brief communication: virological outcomes and dolutegravir resistance mutations in HIV-infected patients: a multicenter retrospective cohort study in Mozambique.
AIDS Res Ther
January 2025
Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
The global HIV epidemic remains a major public health challenge, with DTG playing a key role in ART regimens due to its efficacy and tolerability. This study evaluated virological outcomes and resistance mutations in patients on DTG in Mozambique through a retrospective cohort study in seven DREAM centers. Data from 29,601 patients (98.
View Article and Find Full Text PDFEarly diagnosis of cryptococcal meningoencephalitis in HIV-negative patients: Integration of brain MRI and clinical findings.
eNeurologicalSci
March 2025
Department of Neurology, Brain Research Institute, Niigata University, Japan.
Article Synopsis
- The study focuses on enhancing early diagnosis of cryptococcal meningoencephalitis (CM) in HIV-negative patients to reduce mortality rates.
- Researchers conducted a retrospective analysis of patients with central nervous system infections, highlighting the importance of combining MRI findings with clinical symptoms for accurate diagnosis.
- Key findings showed that specific symptoms and MRI indicators, like the presence of pseudocysts, can significantly improve diagnosis accuracy, leading to better treatment outcomes for patients.
Correlation of Dental and Periodontal Status With HIV Presence and Initial CD4 Counts: An Albanian Prospective Observational Study.
Cureus
December 2024
Infectious Diseases, Faculty of Medicine, University of Medicine, Tirana, ALB.
Background Different pathologies are encountered more often in human immunodeficiency virus (HIV)-infected patients, such as bacterial, fungal, viral infection, and neoplastic diseases. Recently, studies have shown that HIV-infected individuals have poorer oral health outcomes, worse dentition, and aggressive forms of periodontitis. This study aims to investigate the dental and periodontal status of HIV-infected patients, the correlation between CD4+ level and the CD4 percentage with dentition, and periodontal status.
View Article and Find Full Text PDFDrug-Drug Interactions Between HIV Antivirals and Concomitant Drugs in HIV Patients: What We Know and What We Need to Know.
Pharmaceutics
December 2024
Clinical Pharmacology Unit, San Giovanni di Dio e Ruggi d'Aragona University Hospital, 84131 Salerno, Italy.
Highly active antiretroviral therapy has led to a significant increase in the life expectancy of people living with HIV. The trade-off is that HIV-infected patients often suffer from comorbidities that require additional treatment, increasing the risk of Drug-Drug Interactions (DDIs), the clinical relevance of which has often not been determined during registration trials of the drugs involved. Therefore, it is important to identify potential clinically relevant DDIs in order to establish the most appropriate therapeutic approaches.
View Article and Find Full Text PDFEfficacy and safety of an Albuvirtide-based regimen for preventing mother-to-child transmission of multidrug-resistant HIV: a case report.
BMC Pregnancy Childbirth
January 2025
Department of Infectious Diseases, Ganzhou Fifth People's Hospital, Ganzhou, China.
Background: Antiretroviral drugs are essential for preventing mother-to-child transmission (MTCT) of HIV in HIV-infected pregnant women. However, ART treatment for HIV-infected pregnant women with multidrug resistance remains a major challenge. Effective and safe ART regimens for preventing MTCT should be tailored to this special population.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!