Management of severe Budd-Chiari syndrome: report of 147 cases.

Hepatobiliary Pancreat Dis Int

Department of General Surgery, First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China.

Published: November 2004

AI Article Synopsis

  • Budd-Chiari syndrome (BCS) is a rare condition that leads to obstructed blood flow in the liver, and treatments mainly involve surgical or radiological methods.
  • A study analyzed data from 147 severe BCS patients treated at a hospital over nine years, focusing on surgical outcomes.
  • Results indicated that 69.4% of patients had excellent outcomes, while 27.2% had good results after various surgical interventions, with only five fatalities recorded during follow-up.

Article Abstract

Background: Budd-Chiari syndrome (BCS) is an uncommon disorder caused by the obstruction of hepatic venous outflow and/or the inferior vena cava. Major therapeutic approaches include operation and radiological intervention. This study was conducted to investigate the treatment of severe BCS.

Methods: The clinical data of 147 patients with severe BCS who had been treated at our hospital from November 1994 to December 2003 were retrospectively analyzed.

Results: One hundred twenty-one patients with BCS underwent surgery, including mesocaval C type shunt with artificial graft (82 patients), splenojugular shunt (37), mesojugular shunt (2), percutaneous transhepatic recanalization and dilatation and/or stent placement of the main hepatic vein (MHV) (12), and combined percutaneous transhepatic angioplasty (PTA) and stent placement of the inferior vena cava and mesocaval shunt (14). Follow-up for 6-108 months showed excellent results in 102 patients (69.4%), good results in 40 (27.2%), and 5 deaths.

Conclusion: Good results could be obtained in most of patients with BCS after different surgical treatments according to the pathological changes of the IVC and MHV.

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