Geographic information systems (GIS) offer public health nurses a new technology to plan and implement interventions within communities. The present article gives a brief overview of GIS, describes a project designed to pilot-test the use of GIS for developing population-based interventions, and discusses lessons learned from the project that need to be applied to any future work. Using GIS to map the incidence and prevalence of disease, locate risk factors, and identify access to health care services is not difficult. Trying to move beyond that and use the technology to depict community networks and develop and implement population-based interventions is more problematic. The project identified specific questions that anyone involved in a planning or decision-making project in which GIS are used should ask.
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http://dx.doi.org/10.1111/j.0737-1209.2004.21607.x | DOI Listing |
BMC Public Health
January 2025
UMR 1295, Paul Sabatier III University-Inserm, CERPOP: Centre for Epidemiology Research in Population Health, Toulouse, France.
Background: The cardiovascular consequences of night work are increasingly well-known. Implementing effective preventive strategies, however, requires further investigation of the effects of exposure duration. This study sought to assess the cumulative dose-effect of night work exposure on the prevalence of cardiovascular risk factors among current and former night workers in France.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Department of Restorative Dentistry, Periodontology and Endodontology, University Medicine Greifswald, Greifswald, Germany.
Background: Despite considerable improvements in oral health in recent decades, caries and periodontitis are still widespread, ranking among the most prevalent diseases worldwide and requiring future research. The German National Cohort (NAKO Gesundheitsstudie, NAKO) is a large-scaled, multidisciplinary, nationwide, multi-centre, population-based, prospective cohort study with oral examinations that aims to provide a resource to study risk factors for major diseases. The aim of the present article is to provide the methodological background, to report on the data quality, and to present initial results of the oral examinations.
View Article and Find Full Text PDFBMC Bioinformatics
January 2025
Department of Radiology, University of Minnesota, Minneapolis, MN, 55455, USA.
RNA sequencing (RNA-seq) is the conventional genome-scale approach used to capture the expression levels of all detectable genes in a biological sample. This is now regularly used for population-based studies designed to identify genetic determinants of various diseases. Naturally, the accuracy of these tests should be verified and improved if possible.
View Article and Find Full Text PDFNat Med
January 2025
Division of Child Neurology, Reference Center for Neuromuscular Diseases, Department of Pediatrics, CHU Liege, University of Liege, Liege, Belgium.
The rapid development of therapies for severe and rare genetic conditions underlines the need to incorporate first-tier genetic testing into newborn screening (NBS) programs. A workflow was developed to screen newborns for 165 treatable pediatric disorders by deep sequencing of regions of interest in 405 genes. The prospective observational BabyDetect pilot project was launched in September 2022 in a maternity ward of a public hospital in the Liege area, Belgium.
View Article and Find Full Text PDFArch Osteoporos
January 2025
Amgen Inc., Italia 415, 2Nd Floor - Vicente Lopez (1368), Buenos Aires, Argentina.
Unlabelled: Using the UK Clinical Practice Research Datalink, our cohort study matched 237,297 individuals with hearing loss (HL) to 829,431 without HL. The study found an 8-10% higher risk of major osteoporotic fracture in individuals with HL compared to those without. Additionally, within the HL cohort, we identified risk factors for potential inclusion in fracture risk models.
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