10-20% of the men who seek the help of an andrologist present with azoospermia. Possible causes are of genetic origin or are acquired disorders of production and transport. On the basis of a comprehensive andrological work-up this disturbances can be identified. In this connection important parameters for the clarification of azoospermia include patient history, endocrinal laboratory examinations, analysis of the ejaculate and genetic investigations. In addition to medication, microsurgical interventions may be useful. For assisted reproduction, sperm is harvested operatively from the testes or microsurgically from the epididymis.
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