[Experimental study on the microcosmic changes of compressed premaxillary suture with laser scanning confocal microscopy].

Objective: The aim of this experiment is to know whether active orthopedic appliance is rationale to do presurgical treatment and seek some regularities.

Methods: Laser scanning confocal microscopy and triple fluorochrome labeling in bone were used to observe and study detailed changes occurred in compressed suture systematically.

Results: Widened suture and broken fibres between the adjoining bones was observed at the 3rd week postoperatively. At the 3rd week hyperplasia of organic tissue components was also seen. At the 6 and 9th week there were no apparent differences among all groups no matter whether in control group or experimental groups.

Conclusion: Retarding injury of compressed suture and surrounding tissue hyperplasia exists. With growth and development wounded suture will gradually assimilate to control group structurally and functionally.