To determine an antimicrobial action of lactoferrin on bacterial flora of ejaculate in chronic prostatitis, we examined 124 patients with various diseases of male reproductive system at the age between 17 and 56. A total of 280 strains were used as test microorganisms (MO). Sensitivity of the latter to lactoferrin was studied with a human lactoferrin apoform. MO isolated from patients with marked dysbiosis were resistant to lactoferrin (94%). MO, not leading in cenosis, were more sensitive to lactoferrin than MO of the main colonies grown after seeding. Reproductive dysfunction was accompanied by higher occurrence of strains resistant to lactoferrin. The least sensitivity to lactoferrin was registered in asthenozoospermia. Lactoferrin resistance of MO may raise MO pathogenicity. When lactoferrin-resistant strains predominate in microbiocenosis, it is an unfavourable prognostic sign in relation to development of complications, primarily subfertility.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Viscoelastic and flow behaviour of β-lactoglobulin/lactoferrin coacervates: Influence of temperature and ionic strength.
Int J Biol Macromol
December 2024
INRAE, Institut Agro, STLO, 65 Rue de Saint Brieuc, F-35042 Rennes, France.
Heteroprotein complex coacervation has potential for a wide range of applications. However, the sensitivity of coacervates to slight changes in physico-chemical conditions may constitute a technological barrier for their development and deserves to be better understood. In this study, the rheological properties of β-lactoglobulin/lactoferrin (βLG/LF) heteroprotein complex coacervates were investigated with respect to narrow changes of temperature (5-40 °C) and ionic strength (0 to 10 mM added NaCl).
View Article and Find Full Text PDFIn this study, an aptamer biosensor for detecting lactoferrin (LF) was developed using piezoelectric quartz-induced bond rupture sensing technology. The thiol-modified aptamer I was immobilized on the gold electrode surface of the quartz crystal microbalance (QCM) through an Au-S bond to specifically bind LF. It was then combined with aptamer-magnetic beads to amplify the mass signal.
View Article and Find Full Text PDFDetection and quantification of lactoferrin: Innovations, applications, and challenges.
Food Chem
February 2025
Department of Food Materials and Process Design Engineering, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran; Halal Research Center of IRI, Iran Food and Drug Administration, Ministry of Health and Medical Education, Tehran, Iran. Electronic address:
Article Synopsis
- Lactoferrin (LF) is an important glycoprotein involved in various biological functions, including immune defense, tumor inhibition, and possessing antioxidant and antimicrobial properties.
- The review focuses on new analytical methods for detecting LF, discussing both traditional and modern techniques while weighing their pros and cons.
- It highlights advancements in biosensor technology, particularly the role of nanomaterials in improving detection sensitivity and performance, while also addressing ongoing challenges and future potential in LF detection.
Milk Fat Globules: 2024 Updates.
Newborn (Clarksville)
March 2024
Global Newborn Society, Clarksville Maryland, United States of America.
Article Synopsis
- * MFGs feature a unique structure with a lipid core and a membrane rich in bioactive components that aid in energy release and support immune health in developing gastrointestinal tracts.
- * Research suggests MFGs can be enhanced to address specific nutritional deficiencies while also having potential therapeutic benefits for neurodevelopment and defense against infections.
Synergistic effects of antimicrobial components of the human-derived composite amnion-chorion membrane on bacterial growth.
Front Cell Infect Microbiol
October 2024
Department of Periodontics and Dental Hygiene, The University of Texas Health Science Center at Houston School of Dentistry, Houston, TX, United States.
Introduction: The human-derived amnion-chorion membrane (ACM) has endogenous antimicrobial properties, which are important for preventing the colonization and survival of oral bacteria on exposed membranes. This project aimed to decipher the underlying mechanism by identifying the components of ACM that confer antibacterial properties. In addition, the antimicrobial efficacy of these identified components on oral bacteria was assessed.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!