Report on the discovery of a novel 3-hydroxy oxylipin cascade in the yeast Saccharomycopsis synnaedendra.

Prostaglandins Other Lipid Mediat

Department of Microbial, Biochemical and Food Biotechnology, faculty of Natural and Agricultural Sciences, University of the Free State, UNESCO MIRCEN: Industrial Biotechnology, Bloemfontein 9300, South Africa.

Published: October 2004

A novel cascade of 3-hydroxy fatty acids was discovered in the yeast Saccharomycopsis synnaedendra. The cascade, probably derived from incomplete beta-oxidation, comprises both even and uneven carbon numbered as well as saturated and unsaturated 3-hydroxy oxylipins. This yeast may now be used as model to further study the metabolism of these compounds as well as their biotechnological production.

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http://dx.doi.org/10.1016/j.prostaglandins.2004.07.002DOI Listing

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