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  • Chronic intraperitoneal administration of heparin-lysine complex was studied for its impact on blood clotting and insulin systems in young and older rats.
  • The complex positively influenced the balance of coagulant, anticoagulant, and fibrinolytic functions in the hemostatic system, even under conditions of induced diabetes.
  • Both heparin and lysine components of the complex demonstrated significant anti-diabetic properties.

Article Abstract

We studied the effect of chronic intraperitoneal administration of heparin-lysine complex on the state of the hemostatic and insular systems in young and senescent animals (rats). This complex exerted a positive effect on physiological function of the coagulant, anticoagulant, and fibrinolytic components of the hemostatic system in the norm and in developing experimental alloxan diabetes. In this case, both the complex and its components, lysine and heparin, had a pronounced antidiabetogenic effect.

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Article Synopsis
  • Chronic intraperitoneal administration of heparin-lysine complex was studied for its impact on blood clotting and insulin systems in young and older rats.
  • The complex positively influenced the balance of coagulant, anticoagulant, and fibrinolytic functions in the hemostatic system, even under conditions of induced diabetes.
  • Both heparin and lysine components of the complex demonstrated significant anti-diabetic properties.
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