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The Effects of Resigning GPs on Patient Healthcare Utilization and Some Implications for Health.
Health Econ
January 2025
RWI Essen, Essen, Germany.
We study the effects of general practitioners' (GPs') resignations on their patients' healthcare utilization and diagnoses in an event-study setting. Using claims data from a large German statutory health insurance, we find that after physicians leave, their former patients persistently reduce their primary care utilization, only partially substituting it with specialist visits and hospital care. Because patients find a new GP already 1.
View Article and Find Full Text PDFManaging Doxorubicin Cardiotoxicity: Insights Into Molecular Mechanisms and Protective Strategies.
J Biochem Mol Toxicol
February 2025
College of Medicine, Al-Ayen Iraqi University, An Nasiriyah, Iraq.
Cancer ranks as the second leading cause of death in the United States and poses a significant health challenge globally. Numerous therapeutic options exist for treating cancer, with chemotherapy being one of the most prominent. Chemotherapy involves the use of antineoplastic drugs, either alone or in combination with other medications, to target and kill cancer cells.
View Article and Find Full Text PDFMultiorgan Dysfunction and its Association With Congestion and Outcome in Aortic Stenosis Treated With TAVI.
JACC Adv
February 2025
Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.
Background: Degenerative severe aortic stenosis (AS) is treated by valve replacement to improve outcome. Despite diagnostic advancements, many AS patients are still diagnosed late with advanced heart failure.
Objectives: The aim of the study was to assess multiorgan dysfunction in severe AS using blood biomarkers and their association with quantitative fluid levels and clinical outcomes after transcatheter aortic valve implantation (TAVI).
Digital twin driven electrode optimization for wearable bladder monitoring via bioimpedance.
NPJ Digit Med
January 2025
School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Monitoring fluid intake and output for congestive heart failure (CHF) patients is an essential tool to prevent fluid overload, a principal cause of hospital admissions. Addressing this, bladder volume measurement systems utilizing bioimpedance and electrical impedance tomography have been proposed, with limited exploration of continuous monitoring within a wearable design. Advancing this format, we developed a conductivity digital twin from radiological data, where we performed exhaustive simulations to optimize electrode sensitivity on an individual basis.
View Article and Find Full Text PDFA comparative analysis of CNNs and LSTMs for ECG-based diagnosis of arrythmia and congestive heart failure.
Comput Methods Biomech Biomed Engin
January 2025
Centre for Research Impact & Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, Punjab, India.
Cardiac arrhythmias are major global health concern and their early detection is critical for diagnosis. This study comprehensively evaluates the effectiveness of CNNs and LSTMs for the classification of cardiac arrhythmias, considering three PhysioNet datasets. ECG records are segmented to accommodate around ∼10s of ECG data.
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