[Wallenberg's syndrome as the presenting symptom of a cavernous angioma].

Rev Neurol

Servicio de Neurología, Hospital de Bellvitge, L'Hospitalet de Ll., Barcelona, Spain.

Published: May 2005

AI Article Synopsis

  • Cavernous angiomas make up 5-13% of vascular malformations, primarily located in the posterior fossa, often linked with abnormal venous drainage and potentially leading to hemorrhage.
  • A case study discusses a 54-year-old man with symptoms resembling Wallenberg's syndrome, initially misdiagnosed as an ischemic stroke due to normal CT scans, but later identified as a venous angioma through MRI.
  • The study highlights that cavernous angiomas can show no signs of bleeding on scans despite significant symptoms, emphasizing the importance of MRI in differentiating between vascular malformations and ischemic strokes.

Article Abstract

Introduction: Cavernous angiomas account for 5-13% of all vascular malformations. In 75% of cases they are situated in the posterior fossa and up to 30% are associated with abnormal venous drainage. The main complication is haemorrhage; the presence of a neurological focus without radiological evidence of bleeding is very rare.

Case Report: We report the case of a 54-year-old male with cardiovascular risk factors who presented symptoms that progressively deteriorated over a 72-hour period involving the left lower cranial nerves, sensory impairment and coordination disorder, compatible with Wallenberg's syndrome. Two computerised axial tomography scans of the brain were normal and so a tentative diagnosis of ischemic stroke in progression was proposed. Five days later, magnetic resonance imaging (MR) revealed the presence of a venous angioma and associated abnormal venous drainage.

Conclusions: Cavernous angiomas present a dynamic balance between intracavernous bleeding and thrombosis, with very slow venous blood flow. Upsetting this balance leads to an increase in the intracavernous pressure and involvement of the surrounding tissue, with no radiological expression of bleeding. In these cases MR scanning helps to distinguish between a vascular malformation with reduced blood flow and a clinical picture of ischemic stroke of an arterial origin.

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