A total of 400 barrows from Dekalb EB and 83 terminal sires mated to 43 and 45 maternal lines were used to evaluate the effects of dietary ractopamine (RAC; Paylean, Elanco Animal Health, Greenfield, IN) concentrations (0, 5, 10, or 20 ppm; as-fed basis) and feeding durations (6 to 34 d) on growth, efficiency, carcass, and meat quality characteristics of finishing pigs. Barrows were weighed and sorted into five weight blocks, each block consisting of 16 pens (five pigs per pen). Weight blocks were allocated to feeding duration treatments and assigned consecutively by weight from lightest to heaviest to represent 34, 27, 20, 13, and 6 d on test, respectively. The lightest and heaviest blocks averaged 79.8 and 103.8 kg, respectively, at the start of the test. Within a weight block, pens (four per treatment) were randomly assigned to one of four dietary concentrations of RAC in a basal diet containing 18.5% CP and 1.13% lysine. The experiment-wide target slaughter weight was 109 kg, and pigs and feeders were weighed weekly. Weight blocks (80 barrows per block) were slaughtered at a commercial packing plant after 6, 13, 20, 27, or 34 d on test. Overall, RAC supplementation improved (P < 0.05) ADG; however, ADG was not different (P > 0.08) from controls for pigs fed 5, 10, and 20 ppm RAC for 27, 34, and 6 d, respectively. During each feeding period, RAC-fed pigs had improved (P < 0.05) G:F, and, after 20, 27, and 34 d on test, pigs fed 20 ppm RAC had greater (P < 0.05) G:F compared with those fed 0 or 5 ppm RAC. Hot carcass weight was increased (P < 0.05) by RAC feeding after 13 and 27 d of feeding, and by feeding 10 and 20 ppm RAC after 20 d of feeding. After 34 d, pigs fed 20 ppm RAC had heavier (P < 0.05) hot carcass weight than pigs fed 10 ppm RAC. Fat-free lean estimates and the 10th-rib LM area were increased (P < 0.05) by feeding 10 and 20 ppm RAC after 27 d, and by feeding 20 ppm RAC after 34 d compared with controls. Japanese and American color scores, as well as L*, a*, and b* values of the LM, were not affected (P > 0.11) by 5 and 10 ppm RAC compared with controls during each feeding period. Visual marbling score for the LM was decreased (P < 0.05) when RAC was fed at 10 and 20 ppm compared with 0 ppm RAC when fed for 34 d. Dietary RAC improved growth performance at all feeding durations, whereas carcass composition was improved at longer feeding durations. In addition, 5 and 10 ppm RAC did not affect objective and subjective measures of pork quality.
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Environ Sci Pollut Res Int
December 2024
Hazardous Air Pollutants Laboratory, Pakistan Institute of Engineering & Applied Sciences, Islamabad, Pakistan.
Environmentally hazardous radioactive isotopes of iodine may be released from a nuclear power plant as a by-product of uranium fission. The efficient and safe capture of volatile radioiodine is of great significance in the history of nuclear power plants. Due to its high volatility and carcinogenic characteristics, elimination of iodine gas (I) from air is the need of the hour from an environmental and health point of view.
View Article and Find Full Text PDFJ Occup Environ Med
December 2024
From the Program in Physiological Sciences, Institute of Biological Sciences, Federal University of Rio Grande, Rio Grande, RS, Brazil (M.Z.); RAC-Center for Teaching and Research in Animal Reproduction, Faculty of Veterinary Medicine, Federal University of Pelotas, Pelotas, RS, Brazil (A.S.V.J., I.B.A., E.A.d.S., M.E.B.D.); Faculty of Veterinary Medicine, Federal University of Pelotas, Pelotas, RS, Brazil (M.I.G.); UNIPEX-GENOTOX Laboratory (Division of Anesthesiology)-Botucatu Medical School, São Paulo State University-UNESP, Botucatu, SP, Brazil (M.G.B.); and Program in Physiological Sciences, Institute of Biological Sciences, Federal University of Rio Grande, Rio Grande, RS, Brazil (C.D.C.).
Objectives: The aims of the study are to assess the effect of occupational exposure to isoflurane on the sperm quality of mice and to investigate whether cessation of exposure can restore seminal quality.
Methods: Mice were exposed to 50 ppm of isoflurane for 5 hours per day over a 30-day period. Following this exposure, they were euthanized at predetermined postexposure intervals, and their sperm samples were analyzed for kinetics and viability parameters.
Phytomedicine
October 2024
Department of Food Science and Nutrition, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, PR China.; Research Centre for Chinese Medicine Innovation, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, PR China.; State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, PR China.. Electronic address:
Background And Purpose: Icariin, an 8-prenylated flavonoid glycoside, is an anabolic agent that could exert rapid estrogenic actions via ligand-independent activation of estrogen receptor alpha (ERα) in osteoblastic cells to promote osteogenesis. However, relatively little is known about its direct cellular target, its protective effects, and cell adhesion activities in bone marrow stromal cells (BMSCs) against microgravity. In the present study, the effects of icariin on osteogenesis and cell adhesion under microgravity were examined with the involvement of integrin receptor α5β1, connexin 43, and CAMs.
View Article and Find Full Text PDFBiophys Physicobiol
March 2023
Graduate School of Engineering Science, Yokohama National University, Yokohama, Kanagawa 240-8501, Japan.
TAT rhodopsin extracted from the marine bacterium SAR11 HIMB114 has a characteristic Thr-Ala-Thr motif and contains both protonated and deprotonated states of Schiff base at physiological pH conditions due to the low p Here, using solid-state NMR spectroscopy, we investigated the C and N NMR signals of retinal in only the protonated state of TAT in the 1-palmitoyl-2-oleoyl--glycero-3-phosphoethanolamine/1-palmitoyl-2-oleoyl--glycero-3-phospho (1'-rac-glycerol) (POPE/POPG) membrane at weakly acidic conditions. In the C NMR spectrum of C retinal-labeled TAT rhodopsin, the isolated 14-C signals of 13-/15- and 13-/15- isomers were observed at a ratio of 7:3. N retinal protonated Schiff base (RPSB) had a significantly higher magnetic field resonance at 160 ppm.
View Article and Find Full Text PDFACS Omega
December 2023
Department of Chemistry, National Changhua University of Education, 1 Jin-De Road, Changhua City 50007, Taiwan.
Many countries have allowed farmers to feed β-adrenergic receptor agonists, such as ractopamine (Rac), to animals to improve the quality of their meat. However, Rac consumption can cause health problems for humans; thus, detecting Rac in meat before its packaging is essential. Consequently, this study developed a simple and sensitive electrochemical sensor by modifying a glassy carbon electrode (GCE) with Nafion/silver nanoparticles (Nafion/AgNPs).
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