Named entity (NE) recognition has become one of the most fundamental tasks in biomedical knowledge acquisition. In this paper, we present a two-phase named entity recognizer based on SVMs, which consists of a boundary identification phase and a semantic classification phase of named entities. When adapting SVMs to named entity recognition, the multi-class problem and the unbalanced class distribution problem become very serious in terms of training cost and performance. We try to solve these problems by separating the NE recognition task into two subtasks, where we use appropriate SVM classifiers and relevant features for each subtask. In addition, by employing a hierarchical classification method based on ontology, we effectively solve the multi-class problem concerning semantic classification. The experimental results on the GENIA corpus show that the proposed method is effective not only in reducing computational cost but also in improving performance. The F-score (beta=1) for the boundary identification is 74.8 and the F-score for the semantic classification is 66.7.
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http://dx.doi.org/10.1016/j.jbi.2004.08.012 | DOI Listing |
Sci Rep
January 2025
School of Computer Science, Guangdong Polytechnic Normal University, Guangzhou, Guangdong, China.
Knowledge-aware recommendation systems often face challenges owing to sparse supervision signals and redundant entity relations, which can diminish the advantages of utilizing knowledge graphs for enhancing recommendation performance. To tackle these challenges, we propose a novel recommendation model named Dual-Intent-View Contrastive Learning network (DIVCL), inspired by recent advancements in contrastive and intent learning. DIVCL employs a dual-view representation learning approach using Graph Neural Networks (GNNs), consisting of two distinct views: a local view based on the user-item interaction graph and a global view based on the user-item-entity knowledge graph.
View Article and Find Full Text PDFPoult Sci
January 2025
Department of Animal Sciences, Faculty of Agriculture, University of Zabol, Sistan 98661-5538, Iran. Electronic address:
The availability of calcium (Ca) in poultry diets is influenced by various factors, such as the feed ingredients used. This study assessed the apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of Ca in barley and soybean meal (SBM) in young quail chicks using a direct method. Three diets were formulated, including a Ca-free basal diet to evaluate ileal endogenous calcium losses (IECaL), and two diets with barley or SBM as the sole Ca sources.
View Article and Find Full Text PDFJ Am Med Inform Assoc
January 2025
Department of Biomedical Informatics, Columbia University, New York, NY 10032, United States.
Objective: Extracting PICO elements-Participants, Intervention, Comparison, and Outcomes-from clinical trial literature is essential for clinical evidence retrieval, appraisal, and synthesis. Existing approaches do not distinguish the attributes of PICO entities. This study aims to develop a named entity recognition (NER) model to extract PICO entities with fine granularities.
View Article and Find Full Text PDFBioinformatics
January 2025
School of Data Science and Society, University of North Carolina at Chapel Hill, NC 27599, United States.
Motivation: Forecasting the synergistic effects of drug combinations facilitates drug discovery and development, especially regarding cancer therapeutics. While numerous computational methods have emerged, most of them fall short in fully modeling the relationships among clinical entities including drugs, cell lines, and diseases, which hampers their ability to generalize to drug combinations involving unseen drugs. These relationships are complex and multidimensional, requiring sophisticated modeling to capture nuanced interplay that can significantly influence therapeutic efficacy.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
State Key Lab of Geohazard prevention & Geoenvironment protection, College of Materials and Chemistry & Chemical Engineering, Chengdu University of Technology, Chengdu 610059, China. Electronic address:
Sulfur nanoparticles (SNPs) and their composites are promising for heavy metal adsorption, yet current SNPs often lack surface S, leading to low affinity toward heavy metal and ease of aggregation. Here, we report a simple light-driven method for facile prepare SNPs with surfaces enriched with S and in-situ load them onto graphene oxide (GO) to fabricate GO-S composites. Under illumination, the O generated by photosensitizer phloxine B was able to oxidize S into elemental SNPs.
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