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Design of the multicentre randomised controlled BENTO trial to demonstrate patient-relevant benefit of bronchoscopic lung volume reduction using thermal vapour ablation in the German healthcare system for patients with upper lobe emphysema: a study protocol.
BMJ Open
May 2024
Pneumology and Critical Care Medicine, Thoraxklinik am Universitätsklinikum Heidelberg, Heidelberg, Germany.
Introduction: Application of vapour ablation as a novel approach to lung volume reduction has positive effects in patients with severe emphysema. The BENTO study is a randomised, controlled, open, multicentre trial, to assess the effects of bronchoscopic thermal vapour ablation (BTVA) in the German healthcare system.
Methods And Analysis: Patients with bilateral heterogeneous emphysema of the upper lobes in Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage 3/4 will be enrolled in this trial and will receive either standard medical management alone (according to GOLD guidelines) or BTVA treatment with the InterVapor system together with standard medical management.
Innovation in rigid bronchoscopy-past, present, and future.
J Thorac Dis
May 2023
Department of Pulmonary, Allergy and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH, USA.
German laryngologist Gustav Killian performed the first "Direkte Bronchoskopie" using a rigid bronchoscope to extract a foreign airway body from the right main bronchus over a hundred years ago, transforming the practice of respiratory medicine. The procedure instantaneously became popular throughout the world. Chevalier Jackson Sr from the United States further advanced the instrument, technique, safety, and application.
View Article and Find Full Text PDFClinical Impact of Compensatory Hyperinflation of the Nontreated Adjacent Lobe After Bronchoscopic Lung Volume Reduction with Valves.
Int J Chron Obstruct Pulmon Dis
July 2022
Department of Pneumology, University Medicine Essen- Ruhrlandklinik, Essen, Nordrhein-Westfalen, Germany.
Background: Bronchoscopic lung volume reduction (BLVR) with endobronchial valves (EBV) can be a successful treatment for end-stage emphysema patients. The reduction of hyperinflation enhances ventilatory mechanics and diaphragm function. Understanding predictors for treatment success is crucial for further improvements.
View Article and Find Full Text PDFA Novel Two Surgeons Approach to Bronchial Foreign Body Removal by Optical Instruments- An 11 Years Institutional Experience.
Indian J Otolaryngol Head Neck Surg
December 2022
Department of ENT, Choithram Hospital and Research Center, Flat No 902, Block A3, Avasa Housing, opp Phalbag, AB Road, Indore, MP 452012 India.
Unlabelled: A potentially life-threatening emergency in ENT practice is the aspiration of tracheobronchial foreign body. This commonly affects young children and requires early extraction. Successful removal provides immediate relief.
View Article and Find Full Text PDFPredictive value of Chartis measurement for lung function improvements in bronchoscopic lung volume reduction.
Ther Adv Respir Dis
June 2021
Department of Pneumology, University Medicine Essen-Ruhrlandklinik, Essen, Nordrhein-Westfalen, Germany.
Background: Bronchoscopic lung volume reduction (BLVR) valve implantation can be achieved by targeting severely hyperinflated and emphysematously destructed lung areas in patients with chronic obstructive lung disease. Lack of collateral ventilation (CV) is important for good outcomes with BLVR. CV can be measured using the catheter-based Chartis system.
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