Introduction: The authors examined the aortic distensibility indices evaluated by transoesophageal echocardiography (TEE) in patients with ischaemic heart disease and in aortic stenosis cases with normal epicardial coronary arteries.
Patients And Methods: 126 consecutive patients with chest pain were enrolled into the study with the following results: 17 patients showed normal epicardial coronary arteries, 23 patients had non-significant coronary artery disease, 44 patients had significant one-vessel disease and 42 patients had significant multivessel disease. Their results were compared to 16 aortic stenosis cases but with negative coronary angiograms. All patients underwent transthoracic and transoesophageal echocardiography and coronary angiography. During a complete TEE the following data were recorded: systolic and diastolic blood pressure and heart rate, systolo-diastolic aortic diameters and intimo-medial thickness. According to these data elastic and Young's moduli were calculated.
Results: The indices of aortic distensibility were significantly increased (the aortic distensibility was decreased) in patients with coronary artery disease (CAD) as compared to cases with normal epicardial coronary arteries independently the number of affected vessels. In cases of aortic stenosis but with normal epicardial coronary arteries, the aortic distensibility indices were similarly increased as in patients with CAD.
Conclusions: There is a considerable stiffness of the descending aorta of patients with CAD than in cases with normal epicardial coronary arteries. The aortic distensibility of aortic stenosis patients with negative coronary angiograms are similarly decreased that in patients with CAD.
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J Cachexia Sarcopenia Muscle
February 2025
Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Berlin, Germany.
Background: Despite a phenylalanine (Phe) restrictive diet, most adult patients with 'classical' phenylketonuria (PKU) maintain life-long Phe concentrations above the normal range and receive tyrosine (Tyr) and protein-enriched diets to maintain acceptable concentrations and ensure normal development. While these interventions are highly successful in preventing adverse neuropsychiatric complications, their long- term consequences are incompletely explored. We observed early cardiomyopathic characteristics and associated hemodynamic changes in adult PKU patients and present here the results of a longitudinal evaluation of cardiac phenotype.
View Article and Find Full Text PDFJ Vet Diagn Invest
January 2025
Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA.
A 9-y-old, spayed female, non-brachycephalic mixed-breed dog was presented with progressive abdominal distension and diarrhea of <24 h duration. An echocardiogram revealed nodular masses in the pericardium and myocardium, particularly near the auricles. Diagnostic and therapeutic pericardiocentesis failed to improve the dog's status, and the owner elected euthanasia.
View Article and Find Full Text PDFMedicina (Kaunas)
December 2024
Department of Rehabilitation Sciences, College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
: Resistance exercises (REs) are a type of physical activity that individuals from many age groups have been doing recreationally, both as amateurs and professionally, in their daily lives in recent years. It is crucial to understand the effects of such sports on cardiac morphology in order to maximize the benefit of training and to tailor the training content accordingly. The aim of this study was to investigate the relationship between training experience (TE) and left ventricular (LV) systolic and diastolic parameters and left atrial (LA) mechanical function in healthy subjects who regularly performed RE for different durations.
View Article and Find Full Text PDFCardiovasc Ther
January 2025
Institute of Cardiovascular Science, Translational Medicine Institute, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi 710061, China.
Cysteinyl leukotrienes (LTs) and their receptors are involved in the pathogenesis of abdominal aortic aneurysms (AAAs). However, whether CysLT1 receptor antagonists such as montelukast can influence experimental nondissecting AAA remains unclear. Nondissecting AAAs were induced in C57BL/6J mice by transient aortic luminal infusion of porcine pancreatic elastase (PPE).
View Article and Find Full Text PDFEchocardiography
January 2025
Department of Cardiology, Zhejiang Hospital, Hangzhou, Zhejiang, China.
Purpose: There are limited reports on the potential link between Lp(a) and ARDM. Thus, we examined the relationship between Lp(a) and ARDM among hypertensive patients.
Methods: We used echocardiography to measure ARDM in 513 consecutively hospitalized patients.
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