Leading symptoms of anorectal malformation in the neonatal period are abdominal distention, non-passage of meconium and constipation. When present, vomiting is a late symptom. In a study in Calabar, Nigeria, patients were observed to present late, and teenage mothers in rural communities were mostly affected. Female neonates were affected more than males in a ratio of 1.5:1. Classification into low and high abnormality was adopted and proved practical in terms of identification of the pathology and treatment of the lesion. Patients with low abnormality (N = 24, 44.4%) were treated with perineal cut-down, while those with high abnormality (55.6%) had initial palliative colostomy before a definitive abdominal perineal pull-through procedure. Faecal incontinence (13%), anal stenosis (11.1%), constipation (7.4%) and colostomy prolapse (5.6%) were noted to be associated complications. Poverty and ignorance were noted to be the main factors affecting treatment outcome. A concerted public enlightenment campaign is therefore required.
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Interdiscip Cardiovasc Thorac Surg
December 2024
Department of Surgery, University of Port Harcourt, Rivers State, Nigeria.
Objectives: This study accessed the challenges with financing cardiothoracic surgical care in Africa, highlighting the present state of funding, and proffering probable solutions to adequate and effective funding in the region.
Methods: Through a literature review, the authors elaborate on key points such as; areas of financial funding in cardiothoracic surgery, barriers to appropriate allocation of financial resources for cardiothoracic surgery in Africa, and the needs and available resources for cardiothoracic surgery in Africa. Multiple search engines and databases were used, like: PubMed, Medline, Cochrane, Scopus, and Google Scholar.
Viruses
November 2024
Seventh-Day Adventist College of Nursing, Ile-Ife 220103, Nigeria.
The monkeypox outbreak has grown beyond the regions in which it was considered endemic. It has spread from central and west Africa to non-endemic regions like Europe, America, and other parts of the world. It has recently been classified as a public health emergency of international concern.
View Article and Find Full Text PDFJ Diabetes Metab Disord
June 2025
Department of Physiology, Kampala International University, Western Campus, Ishaka, Uganda.
Purpose: Diabetes mellitus is a global health challenge that leads to severe complications, negatively impacting overall health, life expectancy, and quality of life. Herbal medicines, valued for their accessibility and therapeutic benefits with minimal side effects, have been promoted as potential treatments. Managing conditions like diabetes, characterized by free radical production and cytokine-driven inflammation, is vital due to the active components in plants that exert direct pharmacological effects.
View Article and Find Full Text PDFHeliyon
December 2024
Research Centre for Synthesis and Catalysis, Department of Chemical Sciences, University of Johannesburg, South Africa.
[This corrects the article DOI: 10.1016/j.heliyon.
View Article and Find Full Text PDFInfection
January 2025
Department of Medical Microbiology and Immunology, Faculty of Medicine, Gulu University, Gulu, Uganda.
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