[Effect of hemodialysis on peak velocity of early diastolic mitral annulus motion].

Objectives: Peak velocities of early diastolic mitral annulus motion (Ea) assessed by tissue Doppler imaging are relatively preload independent. Whether Ea decreases after hemodialysis or not is unclear. This study investigated the effect of hemodialysis on Ea.

Methods: The study group consisted of 23 hemodialysis patients without organic heart disease. Echocardiography was performed before and after hemodialysis, and Ea was compared with the peak velocity of early mitral inflow (E). Decreases in the body weight, E and Ea were calculated as indexes of decrease by hemodialysis.

Results: After hemodialysis, E decreased significantly (p = 0.005) but Ea did not change (p = 0.09). The decrease in Ea was significantly smaller than that in E (p < 0.0001). The decrease in E correlated significantly (r = 0.52, p < 0.05) with the decrease in the body weight, but the decrease in Ea did not correlate with the decrease in the body weight.

Conclusions: Ea is little affected by hemodialysis compared with E. The effect of hemodialysis on Ea can be ignored if the amount of fluid removal is small.