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Safety and efficacy of transbronchial cryobiopsy for elderly lung cancer patients.
BMC Pulm Med
December 2024
Department of Respiratory Medicine, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, 470-1192, Aichi, Japan.
Background: The increasing prevalence of lung cancer in the elderly population necessitates a closer evaluation of diagnostic and therapeutic approaches. This study aimed to compare the safety and diagnostic efficacy of transbronchial lung cryobiopsy (TBLC) between patients ≥ 80 years and younger patients.
Methods: A retrospective review was conducted of 96 patients diagnosed with peripheral lung cancer who underwent TBLC between April 2021 and October 2023.
Ultrasound-guided transbronchial cryobiopsy of mediastinal and hilar lesions: a multicenter pragmatic cohort study with real-world evidence.
BMJ Open Respir Res
December 2024
Department of Pulmonology, University Hospital Zurich, Zurich, Switzerland
Background: Limited data exist on the reliability, efficacy and safety of ultrasound-guided transbronchial cryobiopsy for suspicious mediastinal and hilar lesions. This study shares findings from implementing this method and compares the results with those of the standard endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA).
Methods: Patients undergoing diagnostic bronchoscopy for mediastinal or hilar lesions in four Swiss centres were included.
Endoscopic ultrasound with bronchoscope-guided transesophageal cryobiopsy: A case series with technical insights, key enablers, and review of literature.
Respirol Case Rep
December 2024
Division of Respiratory Medicine, Department of Medicine Sarawak General Hospital, Jalan Hospital Kuching Malaysia.
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an established technique for lung cancer staging and the diagnosis of mediastinal diseases. Recently, the paradigm of EBUS guided mediastinal sampling with conventional cytology has shifted over to histology specimens through the use of cryobiopsy. This case series explores the novel technique, key enablers, and potential advantages of endoscopic ultrasound with bronchoscope-guided transesophageal cryobiopsy (EUS-B-TEC).
View Article and Find Full Text PDFTransition from Transbronchial Forceps to Cryobiopsy After Lung Transplantation: A Single-Centre Experience.
Life (Basel)
November 2024
Thoracic Surgery and Lung Transplant Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, Italy.
The gold standard for histological acute cellular rejection diagnosis is transbronchial forceps biopsy (FB), but in recent years, transbronchial cryobiopsy (CB) has been increasingly used. This study aims to compare the diagnostic rate and safety of FBs and CBs performed in two different periods. We retrospectively reviewed our case history for the two biopsy procedures: 251 FBs (223 for surveillance purposes and 28 for clinical indication) and 218 consecutive CBs (159 for surveillance purposes and 59 for clinical indication).
View Article and Find Full Text PDF[Diagnostic value and safety of transbronchial cryobiopsy in postoperative complications after lung transplantation].
Zhonghua Jie He He Hu Xi Za Zhi
November 2024
Department of Lung Transplantation, Center of Respiratory Medicine, China-Japan Friendship Hospital, National Center for Respiratory Medicine, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, National Clinical Research Center for Respiratory Diseases, WHO Collaborating Centre for Tobacco Cessation and Respiratory Diseases Prevention, Beijing 100029, China.
Article Synopsis
- A study compared the effectiveness and safety of transbronchial cryobiopsy (TBCB) versus transbronchial lung biopsy (TBLB) for diagnosing postoperative complications in lung transplant patients from June 2017 to June 2024.
- Results showed TBCB had significantly higher pathological (85.7% vs. 45.7%) and clinical diagnosis rates (94.2% vs. 69.9%) compared to TBLB, although both procedures had similar rates of severe complications like bleeding and pneumothorax.
- The most common complications identified after TBCB included chronic lung allograft dysfunction and antibody mediated rejection, whereas TBLB showed higher occurrence of antibody mediated rejection and
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