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Basic Science and Pathogenesis.
Alzheimers Dement
December 2024
Université Laval, Quebec, QC, Canada.
Background: There is a common agreement that Alzheimer's disease (AD) is inherently complex; otherwise, a general disagreement remains on its etiological underpinning, with numerous alternative hypotheses having been proposed. Our objective was to perform a scoping review of original manuscripts describing hypotheses and theories of AD published in past decades.
Methods: We reviewed 127 original manuscripts that fulfilled our inclusion criteria out of more than 13,807 references extracted from open databases (from inception to 14 Sept 2023).
An adaptive protocol to assess physiological responses as a function of task demand in speech-in-noise testing.
J Neurosci Methods
December 2024
Politecnico di Milano, Piazza Leonardo da Vinci, 32, Milan, 20133, Italy. Electronic address:
Background: Acoustic challenges impose demands on cognitive resources, known as listening effort (LE), which can substantially influence speech perception and communication. Standardized assessment protocols for monitoring LE are lacking, hindering the development of adaptive hearing assistive technology.
New Method: We employed an adaptive protocol, including a speech-in-noise test and personalized definition of task demand, to assess LE and its physiological correlates.
Over the past 160 years, the UK has experienced significant winter mortality among older people. A quarter of a million older people have died from cold-related illnesses over the past decade, with one older person dying every seven minutes. Misconceptions about winter deaths must be addressed.
View Article and Find Full Text PDFResearch on multi-label recognition of tongue features in stroke patients based on deep learning.
Sci Rep
December 2024
Hunan University of Chinese Medicine, Changsha, China.
Stroke has become the leading cause of disability in adults worldwide. Early precise rehabilitation intervention is crucial for the recovery of stroke patients, with the key lying in accurately identifying patients' physical characteristics during the rehabilitation phase. Compared to diagnostic techniques such as medical neuroimaging, traditional Chinese medicine(TCM) tongue diagnosis offers good accessibility and ease of application.
View Article and Find Full Text PDFPlasticity syndromes in wild vertebrates: Patterns and consequences of individual variation in plasticity across multiple behaviours.
Ecol Lett
December 2024
Department of Biology, Center for Ecosystem Sentinels, University of Washington, Seattle, Washington, USA.
Behavioural plasticity is an important mechanism allowing animals to cope with changing environments. Theory has hypothesized the existence of 'plasticity syndromes'-positive correlations in plasticity across multiple behaviours within an individual-affording a generalized ability to respond to environmental change. However, the occurrence of correlated plasticities and their potential fitness consequences in natural populations remain untested.
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