Objectives: There is little information available about the prevalence of chronic metabolic diseases in many Latin American countries. Between 1995 and 1998, studies on the prevalence of obesity, hypertension, hyperlipidemia and diabetes were carried out in four cities located in central Argentina: Dean Funes, Oncativo, Pehuajo and Venado Tuerto. The data provided by these surveys are reanalysed here in order to determine prevalence of obesity, hypertension, hyperlipidemia and diabetes using new epidemiological criteria.
Methods: Representative samples of the population, based on a multistage probabilistic sampling design, were taken from each of the four cities. The sample size was calculated to obtain a precision of 4% for the prevalence assessment. The subjects included were aged 20 years and over. Standardization of the prevalence rates used the entire study sample as the reference population.
Results: Age-standardised prevalence rates for the cities ranged between 22.4% and 30.8% for obesity, 27.9% and 43.6% for hypertension, 24.2% and 36.4% for hyperlipidemia, and 6.5% and 7.7% for diabetes mellitus. All these prevalences increased with age. 58.1% of the obese subjects and 51.2% of the diabetic subjects had hypertension, while 43.2% of the obese subjects and 52.8% of the diabetic subjects had hyperlipidemia.
Conclusions: While the prevalence of diabetes mellitus was between 6% and 8%, the prevalence of obesity was close to 26% and hypertension and hyperlipidemia affected one third of the population. These data can be considered as indicative of the prevalences of these four diseases in the population aged 20 years and over, in the central region of Argentina.
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http://dx.doi.org/10.1016/s1262-3636(07)70125-8 | DOI Listing |
J Cardiovasc Transl Res
January 2025
Cardiac Regeneration and Ageing Lab, Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong, 226011, China.
HFpEF is a prevalent and complex type of heart failure. The concurrent presence of conditions such as obesity, hypertension, hyperglycemia, and hyperlipidemia significantly increase the risk of developing HFpEF. Mitochondria, often referred to as the powerhouses of the cell, are crucial in maintaining cellular functions, including ATP production, intracellular Ca regulation, reactive oxygen species generation and clearance, and the regulation of apoptosis.
View Article and Find Full Text PDFJ Prev Alzheimers Dis
February 2025
Turku PET Centre, University of Turku, Turku, Finland; Turku PET Centre, Turku University Hospital, Turku, Finland; Department of Geriatrics, Turku University Hospital, Wellbeing services county of Southwestern Finland, Finland.
Background: Dementia is a significant cause of disability and dependency. Persons with high dementia risk but intact cognition will benefit from preventive interventions.
Objectives: The aim was to validate dementia risk score Cardiovascular Risk Factors, Aging and Incidence of Dementia (CAIDE) in a national population-based cohort with data on age, education, hypertension, obesity, hyperlipidemia and physical activity.
Nutrients
January 2025
Department of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Background/objectives: Chronic gut dysbiosis due to a high-fat diet (HFD) instigates cardiac remodeling and heart failure with preserved ejection fraction (HFpEF), in particular, kidney/volume-dependent HFpEF. Studies report that although mitochondrial ATP citrate lyase (ACLY) supports cardiac function, it decreases more in human HFpEF than HFrEF. Interestingly, ACLY synthesizes lipids and creates hyperlipidemia.
View Article and Find Full Text PDFBiology (Basel)
December 2024
Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Chronic kidney disease (CKD) is a global health concern caused by conditions such as hypertension, diabetes, hyperlipidemia, and chronic nephritis, leading to structural and functional kidney injury. Kidney fibrosis is a common outcome of CKD progression, with abnormal fatty acid oxidation (FAO) disrupting renal energy homeostasis and leading to functional impairments. This results in maladaptive repair mechanisms and the secretion of profibrotic factors, and exacerbates renal fibrosis.
View Article and Find Full Text PDFMaturitas
January 2025
Elderly Frailty Research Center, Department of Family Medicine, College of Medicine, Kyung Hee University, Kyung Hee University Medical Center, Seoul 02447, Republic of Korea. Electronic address:
Background: Muscle mass loss and fat mass increase are risk factors for cardiometabolic disease. We evaluated the effect of changes in body composition on the incidence of cardiometabolic diseases in older adults with or without sarcopenia, over two-year follow-up.
Materials And Methods: Changes in body composition and the development of cardiometabolic diseases over 2 years were measured in community-dwelling older adults recruited from the Korean Frailty Aging Cohort Study.
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