[Common variable immunodeficiency and celiac disease].

Gastroenterol Clin Biol

Service de Clinique Médicale, Hôpital du Val de Grâce, 74 boulevard de Port Royal, 75230 Paris Cedex 05.

Published: October 2004

Variable immunodeficiency is frequently associated with subtotal villous atrophy, unchanged by gluten free diet. We report two cases of common variable immunodeficiency associated with chronic symptoms of malabsorption due to total villous atrophy. Symptoms of malabsorption disappeared and histological abnormalities improved after a gluten free diet. The association between celiac disease and common variable immunodeficiency should not be considered as fortuitous. Clinicians should be aware of this association and of the low sensitivity of serologic testing in this setting.

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http://dx.doi.org/10.1016/s0399-8320(04)95157-3DOI Listing

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