Systematic review of the evidence supporting intra-oral maxillofacial prosthodontic care.

The literature on maxillofacial prosthodontics may be considered to be dominated by articles describing case reports or case series. Prospective, well-controlled clinical trials are scarce owing to the inherent difficulty of performing such trials in patients suffering from oral cancer. The aim of this study was to perform a systematic review of the literature relating to intra-oral maxillofacial prosthodontics based on the principles of evidence-based dentistry. A detailed report of the findings is presented and critically assessed and a discussion of the outcome in respect to the various confounding factors is carried out. Finally, suggestions for future research in the field of maxillofacial prosthodontics are made.