A level-set method, specifically conceived for the case of soft organic tissue growth from feeding solutions, is introduced and described in detail. The model can handle the morphological evolution of the organic specimen under the influence of external convection (fluid-dynamics of the bioreactor). The analogies and differences between this technique and a previous volume of fraction method are discussed pointing out advantages and limitations of both formulations.
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| http://dx.doi.org/10.1016/j.jbiomech.2004.02.037 | DOI Listing |
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