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[Clinical significance of molecular classification and hereditary phenotypic characteristics in endometrial carcinoma].
Zhonghua Zhong Liu Za Zhi
January 2025
Department of Pathology, China-Japan Friendship Hospital, Beijing100029, China.
To analyze the clinical significance of molecular classification and hereditary phenotype in endometrial carcinoma (EC) based on high throughput sequencing (NGS). 97 EC samples were collected retrospectively from December 2019 to October 2022 in China-Japan Friendship Hospital. NGS technique was used to analyze the molecular classification, POLE hypermutation, microsatellite high Instability/mismatch repair dysfunction (MSI-H/MMRd), P53 protein abnormality (P53 abn), and non-specific molecular profile (NSMP).
View Article and Find Full Text PDFEpidemiological and molecular characterization of investigation of Mycoplasma gallisepticum of goose origin in Guangdong (China).
Poult Sci
January 2025
School of Agricultural and Biological Engineering, Foshan University, Foshan 528225, China. Electronic address:
The Guangdong region is the largest goose farming area in China, which has experience significant economic losse due to the epidemic of Mycoplasma gallisepticum (MG) infection in geese. This study addresses the critical gap in epidemiological data on the prevalence of MG infection in geese, which seriously hinders the diagnosis and treatment. We collected respiratory system samples from geese displaying respiratory symptoms, isolated and identified Mycoplasma species, and confirmed MG presence through PCR.
View Article and Find Full Text PDFPhylogenetic analysis of termite-associated Xylaria from Africa reveals hidden diversity.
Fungal Biol
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Section for Ecology and Evolution, Department of Biology, University of Copenhagen, 2100 Copenhagen East, Denmark. Electronic address:
Fungus-farming termite colonies host members of the genus Xylaria as stow-away fungi that emerge from deteriorating fungal gardens (combs) or dying termite nests. Fungus-farming termites originated in Africa, where the highest host diversity - eleven termite genera - exists, and later colonised parts of Asia, where five extant termite genera are known. Theory predicts that symbiont diversity should correlate with host diversity, but while 17 termite-associated Xylaria species have been described from Asia, a mere three African species have been formally described.
View Article and Find Full Text PDFDNA-based cell typing in menstrual effluent identifies cell type variation by sample collection method: toward noninvasive biomarker development for women's health.
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Department of Anthropology, Dartmouth College, Hanover, NH, USA.
Menstrual effluent cell profiles have potential as noninvasive biomarkers of female reproductive and gynecological health and disease. We used DNA methylation-based cell type deconvolution (methylation cytometry) to identify cell type profiles in self-collected menstrual effluent. During the second day of their menstrual cycle, healthy participants collected menstrual effluent using a vaginal swab, menstrual cup, and pad.
View Article and Find Full Text PDFDetection of Francisellaceae and the differentiation of main European F. tularensis ssp. holarctica strains (Clades) by new designed qPCR assays.
BMC Microbiol
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Cellular Interactions of Bacterial Pathogens, Centre for Biological Threats and Special Pathogens, Highly Pathogenic Microorganisms (ZBS 2), Robert Koch Institute, Seestraße 10, 13353, Berlin, Germany.
Background: The zoonotic and highly infectious pathogen Francisella tularensis is the etiological agent of tularemia. Tularemia in humans is mainly caused by F. tularensis subspecies tularensis and holarctica, but Francisella species like F.
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