This paper provides an overview of recent results derived from the accident history data collected under 112(r) of the Clean Air Act Amendments (the Risk Management Program (RMP) Rule) covering the period 1994-2000, together with a preliminary assessment of the effectiveness of the RMP Rule as a form of Management System Regulation. These were undertaken at the University of Pennsylvania by a multi-disciplinary team of economists, statisticians and epidemiologists with the support of the US Environmental Protection Agency and its Office of Emergency Prevention, Preparedness and Response (OEPPR, formerly CEPPO). Section 112(r) of the Clean Air Act Amendments of 1990 requires that chemical facilities in the US that had on premises more than specified quantities of toxic or flammable chemicals file a 5-year history of accidents. The initial data reported under the RMP Rule covered roughly the period from mid-1994 through mid-2000, and provided details on economic, environmental and acute health affects resulting from accidents at some 15,000 US chemical facilities for this period. This paper reviews research based on this data. The research is in the form of a retrospective cohort study that considers the statistical associations between accident frequency and accident severity at covered facilities (the outcome variables of interest) and a number of facility characteristics (the available predictor variables provided by the RMP Rule), the latter including such facility characteristics as size, hazardousness, financial characteristics of parent company-owners of the facility, regulatory programs in force at the facility, and host community characteristics for the surrounding county in which the facility was located, as captured in the 1990 Census. Among the findings reviewed are: (1) positive associations with (a measure of) facility hazardousness and accident, injury and economic costs of accidents; (2) positive (resp., negative) associations between accident propensity and debt-equity ratios (resp., sales) of parent companies; (3) several interrelated associations between accident propensity and regulatory programs in force; and (4) strong associations between facility hazardousness, facility locations decisions, observed accident frequencies and community demographics.
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http://dx.doi.org/10.1016/j.jhazmat.2004.06.016 | DOI Listing |
Anal Bioanal Chem
January 2025
Chemical Sciences Division, National Institute of Standards and Technology (NIST), Gaithersburg, MD, 20899, USA.
Commutability is where the measurement response for a reference material (RM) is the same as for an individual patient sample with the same concentration of analyte measured using two or more measurement systems. Assessment of commutability is essential when the RM is used in a calibration hierarchy or to ensure that clinical measurements are comparable across different measurement procedures and at different times. The commutability of three new Standard Reference Materials (SRMs) for determining serum total 25-hydroxyvitamin D [25(OH)D], defined as the sum of 25-hydroxyvitamin D [25(OH)D] and 25-hydroxyvitamin D [25(OH)D], was assessed through an interlaboratory study.
View Article and Find Full Text PDFFront Cell Dev Biol
May 2022
Departamento de Física Médica, Centro Atómico Bariloche, Comisión Nacional de Energía Atómica, San Carlos de Bariloche, Argentina.
New Solut
February 2022
University of Massachusetts Lowell, Lowell, USA.
The Trump administration weakened regulations through changes on rules that have been improved during the Obama years. An example is the reversal in 2019 of the improvements to the U.S.
View Article and Find Full Text PDFNiger Postgrad Med J
August 2020
Department of Surgery, College of Medicine, University of Lagos; Lagos University Teaching Hospital, Idi-Araba; Journal Unit, National Postgraduate Medical College of Nigeria, Ijanikin, Lagos, Nigeria.
Research misconduct policy (RMP) is a legal document that shows the definitions of the various types of misconduct, describes the inquiry and investigation of allegations, and the appropriate penalties that should be imposed. The presence of the adopted RMP on the website of a university or postgraduate college is an indication of the level of commitment to promote the proper handling of misconduct cases. Perusal of the websites of top universities in developing countries revealed that many do not have RMP on their websites.
View Article and Find Full Text PDFForensic Sci Int Genet
November 2019
Department of Genetics & Genome Biology, University of Leicester, Leicester, UK. Electronic address:
While many studies have been undertaken of Middle Eastern populations using autosomal STR profiling by capillary electrophoresis, little has so far been published from this region on the forensic use of massively parallel sequencing (MPS). Here, we carried out MPS of 27 autosomal STRs and 91 identity-informative SNPs (iiSNPs) with the Verogen ForenSeq™ DNA Signature Prep Kit on a representative sample of 89 Saudi Arabian males, and analysed the resulting sequence data using Verogen's ForenSeq Universal Analysis Software (UAS) v1.3 and STRait Razor v3.
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