Objective: To establish mean and reference range of basal serum inhibin B levels in a group of healthy fertile Bulgarian women.

Methods: The present report covers the results of 9 month's period in which sixty-five healthy fertile Bulgarian women, aged 20-40 years were selected to determinate a reference group of healthy fertile women with normal values of inhibin B. Blood samples were collected on early follicular phase of menstrual cycle (2-4 days). Inhibin B was analyzed in duplicate with the use of a double-antibody ELISA.

Results: We established mean values of inhibin B 121.22 (+/- 45.04) pg/ml in a group of 65 healthy fertile Bulgarian women with mean 30.78 (+/- 3.94) years of age. The values of inhibin-B, which we obtained in the 5th percentile, was 33.15 pg/ml and in the 95th percentile was 190.75 pg/ml.

Conclusions: The measurement of inhibin B is a test easy for performance, with reference values for healthy fertile Bulgarian women between 33.15 pg/ml and 190.75 pg/ml.

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