Antibiotic activity screening of some species of genus Aspergillus (64 strains) to different test-organisms (gram positive, gram negative, phytopathogenic bacteria and yeasts) has been carried out. The researched strains A. parvulus, A. ochraceus, A. ustus, A. versicolor, A.fumigatus, A. niger, A. deflectus, A. clavatus were characterized by a wide spectrum of antibiotic activity; the strains A. flavipes, A. sydowii, A. terreus, A. flavus, A. nidulans, A. alliaceus, A. fluticulosus were characterized by a narrow spectrum of antibiotic activity. Fungistatic activity was shown for some strains of A. ochraceus, A. versicolor, A. ustus. The majority of investigated strains were characterized by the static action. The species A. parvulus which has not been investigated before is distinguished by a wide spectrum of antibiotic activities would be recognized most interesting for further investigation.

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