Aziridine sulfides and disulfides as catalysts for the enantioselective addition of diethylzinc to aldehydes.

Chem Commun (Camb)

Departamento de Química, Universidade Federal de Santa Maria, 97105-900-Santa Maria-RS, Brazil.

Published: November 2004

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Article Abstract

Chiral aziridine sulfides and disulfides were synthesized from readily available and inexpensive R-cysteine by a Mitsunobu reaction; their application in the addition of diethylzinc to aldehydes provides secondary alcohols with up to 99% ee and S-configuration.

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http://dx.doi.org/10.1039/b408537jDOI Listing

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