Improvement in surgical techniques has led to improved anatomic and functional success rates following surgery for severe complications of proliferative diabetic retinopathy (PDR). We compared the anatomic and functional outcomes of surgery in a non-randomized, consecutive case series of patients with severe PDR. We found that viscodissection using Healon provides outcomes comparable to conventional pick and scissors dissection. We also found that adjunctive use of silicone oil can salvage selected cases with particularly severe manifestations of PDR (e.g., the fibrinoid syndrome). With proper selection of patients and techniques, the anatomic success rate can exceed 80% even in the most severe cases. The goal of this paper is to show the applicability of using viscodissection and silicone oil infusion during vitrectomy in eyes with severe PDR.
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http://dx.doi.org/10.1076/soph.18.3.121.29811 | DOI Listing |
ACS Appl Mater Interfaces
January 2025
State Key Laboratory of Polymer Materials Engineering, College of Polymer Science and Engineering, Sichuan University, Chengdu, Sichuan 610065, P.R. China.
Silicone rubber (SR) holds significant potential for everyday wearable devices due to its inherent sweat resistance and flexibility. However, its broader applicability is constrained by poor oil resistance and a suboptimal slip performance. In this study, we developed an SR with durable oil resistance and enhanced slip properties by forming a covalently bonded barrier layer on its surface through a one-step in situ fluorination reaction using F/N.
View Article and Find Full Text PDFPolymers (Basel)
January 2025
HKUST Shenzhen-Hong Kong Collaborative Innovation Research Institute, Futian, Shenzhen 518000, China.
The effectiveness of ultraviolet-C light-emitting diodes (UVC LEDs) is currently limited by the lack of suitable encapsulation materials, restricting their use in sterilization, communication, and in vivo cancer tumor inhibition. This study evaluates various silicone oils for UVC LED encapsulation. A material aging experiment was conducted on CF1040 (octamethylcyclotetrasiloxane), HF2020 (methyl hydro polysiloxanes), and MF2020-1000 (polydimethylsiloxane) under UVC radiation for 1000 h.
View Article and Find Full Text PDFMicromachines (Basel)
January 2025
School of Chemical Engineering, University of Birmingham, Birmingham B15 2TT, UK.
This study evaluates the performance of continuous flow and drop-based microfluidic devices for the synthesis of silver nanoparticles (AgNPs) under identical hydrodynamic and chemical conditions. Flows at low values of Dean number (De < 1) were investigated, where the contribution of the vortices forming inside the drop to the additional mixing inside the reactor should be most noticeable. In the drop-based microfluidic device, discrete aqueous drops serving as reactors were generated by flow focusing using silicone oil as the continuous phase.
View Article and Find Full Text PDFInt Ophthalmol
January 2025
The University of Adelaide, North Terrace, Adelaide, SA, 5000, Australia.
Purpose: To characterize the anterior segment (AS) morphology of patients with long-term silicone oil (SiO) in situ (> 12 months) following pars plana vitrectomy (PPV).
Methods: This prospective, comparative characterization study was conducted between January 2022 and July 2023. Patients were included and sorted based on if they had undergone PPV without long-term SiO or had SiO in situ for at least 12 months at the time of review and image collection.
Ocul Immunol Inflamm
January 2025
Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Purpose: To observe the changes in the axial length (AL) in patients of acute retinal necrosis (ARN) undergoing vitrectomy and investigate the correlated factors.
Methods: Retrospective case series. Patients diagnosed as ARN undergoing vitrectomy with silicone oil (SO) tamponade, and with attached retina more than one year after silicone oil removal (SOR) were included.
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