Hand preference and skill were assessed in 27 children with Fragile-X syndrome, 30 children with Down's Syndrome, and 29 normal developing children. Three separate and specific anomalies of handedness that have been reported in other learning-disordered groups were examined: increased incidence of left-handedness; ambiguous or inconsistent handedness; and preference-skill discordance. The results revealed no difference between the subject groups in the distribution of left-handedness or ambiguous handedness. The main differences was the percentage of children who were discordant for hand preference and hand skill. In the Fragile-X group 37% preferred to use their right hand but demonstrated no overall difference in skilled performance between the hands. In contrast, only 13% of children with Down's Syndrome and 17% of normal controls showed this pattern of hand discordance. The results are discussed in the context of past research that has shown a similar dissociation of preference and skill in children with autism.
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http://dx.doi.org/10.1080/713754261 | DOI Listing |
Magn Reson Imaging
December 2024
Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China. Electronic address:
Purpose: To evaluate cerebrospinal fluid (CSF) flow dynamics and volume changes of pulsatile tinnitus (PT) patients induced by sigmoid sinus wall dehiscence (SSWD) with intracranial hypertension.
Methods: Thirty-five SSWD-PT patients coexisted with intracranial hypertension and 35, age-, gender-, and handedness-matched healthy volunteers were prospectively enrolled and performed MRI. Clinical data were collected.
Nat Commun
November 2024
Department of Physics, The City College of New York-CUNY, New York, NY, 10031, USA.
Chirality - a characteristic handedness that distinguishes 'left' from 'right'-is a fundamental property of quantum particles under broken symmetry intimately connected to their spins. Chiral fermions have been identified in Weyl semimetals through their unique electrodynamics arising from 'axial' charge imbalance between pairs of chiral Weyl nodes-the topologically protected 'relativistic' crossings of electronic bands. Chiral magnetotransport phenomena critically depend on the details of electronic band structure.
View Article and Find Full Text PDFBrain Res Bull
November 2024
Lab of Digital Image and Intelligent Computation, Shanghai Maritime University, Shanghai 201306, China.
Research on the neural mechanisms underlying brain asymmetry in patients with migraine patients using fMRI is insufficient. This study proposed using lateralized algorithms for functional connectivity and brain network topology and investigated changes in their lateralization in patients with migraine. In study 1, laterality indices of functional connectivity (LFunctionCorr) and brain network topological properties (LBetweennessCentrality, LDegree, and LStrength) were defined.
View Article and Find Full Text PDFJ Affect Disord
January 2025
School of Mental Health and Psychological Sciences, Anhui Medical University, 81 Meishan Rd, Hefei 230032, China; Department of Psychology and Sleep Medicine, The Second Affiliated Hospital of Anhui Medical University, Anhui Medical University, Hefei, China; Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders, Hefei, China; Collaborative Innovation Centre of Neuropsychiatric Disorder and Mental Health, Hefei, China; Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, China; Anhui Institute of Translational Medicine, Hefei, China. Electronic address:
Background: Hemispheric lateralization and cooperation are essential for efficient brain function, and aberrations in both have been found in psychiatric disorders such as schizophrenia. This study investigated alterations in hemispheric lateralization and cooperation among patients with bipolar disorder (BD) and associations with neurotransmitter and cell-type density distributions to identify potential molecular and cellular pathomechanisms.
Methods: Sixty-seven BD patients and 127 healthy controls (HCs) were examined by resting-state functional MRI (rs-fMRI).
J Zhejiang Univ Sci B
February 2024
Gansu Provincial Key Laboratory of Wearable Computing, School of Information Science and Engineering, Lanzhou University, Lanzhou 730000, China.
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