Forty adult female rats were randomly divided into four groups. Before the standard surgical procedure which consisted of creating a lesion with a lancet over the right uterine horn. Group I received no medication. Ringer's lactate (RL) solution was applied intraperitoneally to Group II at the end of the surgery. Sepracoat solution was applied intraperitoneally to Group III at the onset of the surgery. Group IV randomly received Seprafilm wrapped over the entire right uterine horn. Re-laparotomy was performed 3 weeks later to evaluate the adhesions. The mean adhesion scores were (mean+/-SD) 2.90+/-0.18, 1.00+/-0.36, 0.50+/-0.17 and 0.40+/-0.16 in Groups I, II, III, IV, respectively. The postsurgical adhesions were significantly less in the groups treated with Seprafilm and Sepracoat.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/01443610063543 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Antimicrobial Efficacy of Five Wound Irrigation Solutions in the Periprosthetic Joint Infection Microenvironment In Vitro and Ex Vivo.
Antibiotics (Basel)
January 2025
Department of Dermatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Periprosthetic joint infections (PJI) are difficult to treat due to biofilm formation on implant surfaces and the surrounding tissue, often requiring removal or exchange of prostheses along with long-lasting antibiotic treatment. Antiseptic irrigation during revision surgery might decrease bacterial biofilm load and thereby improve treatment success. This in vitro study investigated and compared the effect of five advanced wound irrigation solutions to reduce bacterial burden in the PJI microenvironment.
View Article and Find Full Text PDFHigh-volume lactated Ringer's solution with human albumin versus standard-volume infusion as a prophylactic treatment for post-endoscopic retrograde cholangiopancreatography pancreatitis: randomized clinical trial.
BJS Open
December 2024
Department of Surgery, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Background: Adverse events after endoscopic retrograde cholangiopancreatography (ERCP) are rare, and post-ERCP pancreatitis is a serious adverse event. This study aimed to determine the role of aggressive intravenous hydration with lactated Ringer's solution at a specific volume with 20% human albumin before ERCP in reducing the incidence of post-ERCP pancreatitis.
Methods: This study was a single-centre randomized clinical trial.
Effect of isotonic sodium bicarbonate infusion on perioperative acid-base status among patients undergoing emergency laparotomy for perforation peritonitis (ISABEL trial): a randomized controlled trial.
Eur J Trauma Emerg Surg
January 2025
Department of Anaesthesia & Intensive Care, Postgraduate Institute of Medical Education and Research (PGIMER), Sector-12, Chandigarh, 160012, India.
Purpose: Perioperative metabolic acidosis negatively affects patient outcomes. Perioperative fluid therapy has a clinically significant effect on acid-base balance. This study was conducted to evaluate the effects of isotonic sodium bicarbonate infusion (ISB) versus balanced crystalloid solution (BCS) on perioperative acid-base balance, in terms of postoperative base excess, among patients undergoing emergency laparotomy for perforation peritonitis.
View Article and Find Full Text PDFVolume of intraoperative normal saline versus lactated Ringer's solution on acute kidney injury: A secondary analysis of the SOLAR trial.
J Clin Anesth
February 2025
Center for Outcomess Research and Department of Anesthesiology, UTHealth, Houston, TX, United States of America. Electronic address:
Unlabelled: Postoperative acute kidney injury (AKI) is common after non-cardiac surgery. Normal saline and lactated Ringer's solution are both used for volume replacement during surgery. Normal saline decreases renal blood flow and causes hyperchloremic acidosis whereas lactated Ringer's does not.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!