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Research progress of femoral head necrosis in HIV-infected patients.
Ann Med
December 2025
Department of Joint and Sports Medicine, Zhongnan Hospital, Wuhan University, Wuhan, China.
As life expectancy among patients infected with the human immunodeficiency virus (HIV) increases, a growing number of complications have been observed. This population displays an elevated risk of ischemic necrosis of the femoral head in comparison to the general population, which may be attributed to HIV infection, antiretroviral medication use, and hormone application. Patients infected with the human immunodeficiency virus (HIV) who also have necrosis of the femoral head tend to present at an earlier age, with a rapid disease progression and a high incidence of bilateral onset.
View Article and Find Full Text PDFEarly intervention in eating disorders: introducing the chronopathogram.
Eat Weight Disord
January 2025
Eating Disorders Unit, Department of Neuroscience, University of Turin, Via Cherasco 15, 10126, Turin, Turin, Italy.
Eating disorders (EDs) pose significant challenges to mental and physical health, particularly among adolescents and young adults, with the COVID-19 pandemic exacerbating risk factors. Despite advancements in psychosocial and pharmacological treatments, improvements remain limited. Early intervention in EDs, inspired by the model developed for psychosis, emphasizes the importance of timely identification and treatment initiation to improve prognosis.
View Article and Find Full Text PDFUncomplicated pharyngitis due to family transmission of hypervirulent Klebsiella pneumoniae.
Eur J Clin Microbiol Infect Dis
January 2025
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
We describe two cases of uncomplicated pharyngitis caused by hypervirulent Klebsiella pneumoniae (hvKp) in a family, initially in an immunocompetent adolescent, followed by possible household spread resulting in similar presentations in the patient's parent. Genomic analysis confirmed hvKp from the two cases were genetically identical and typed as K2-ST3252. Nasopharyngeal carriage and respiratory secretion/droplet may play an important yet underrecognized role in the transmission of hvKp.
View Article and Find Full Text PDFExhalation of Rn-219 by patients treated with Radium-223.
EJNMMI Phys
January 2025
Department for Radiation Protection and Medical Physics, Hannover Medical School, Carl-Neuberg- Str. 1, 30625, Hannover, Germany.
Background: Treatment with Ra-223 dichloride is approved for the therapy of castration resistant prostate cancer (CRPC) with symptomatic bone metastases and no known visceral metastases in Europe since 2013, and Ra-223 is under discussion for labelling other molecules and nanoparticles. The direct progeny of Ra-223 is Rn-219, also known as actinon, a radioactive noble gas with a half-life of 3.98 s.
View Article and Find Full Text PDFMultimorbidity and Depressive Symptoms and their Association with Self-Reported Health and Life Satisfaction Among Adults Aged ≥ 50 Years in Mexico.
J Cross Cult Gerontol
January 2025
Departamento de Atención a la Salud, Universidad Autónoma Metropolitana Xochimilco, CDMX, Mexico.
Identify the association between multimorbidity and depressive symptoms (DS) with self-reported health (SRH) and life satisfaction in a national sample of Mexican ≥ 50 years older adults. Data are drawn from the Mexican Health and Aging Study (MHAS), a cross-sectional study conducted in 2018 involving 14,230 older adults aged 50 years and older living in urban and rural areas of Mexico. Depressive symptoms were measured using the Center for Epidemiological Studies depression scale (CES-D) and life satisfaction using the Life Satisfaction Scale (LSS), examined both as a categorical and continuous variable.
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