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Improved MR Detection of Optic Nerve Demyelination With MP2RAGE-FLAWS Compared With T2-Weighted Fat-Saturated Sequences.
Invest Radiol
November 2024
From the Department of Neuroradiology, AP-HP, Henri Mondor University Hospital, Créteil, France (R.A., T.E., I.M., B.B.); University Paris Est Créteil, INSERM, IMRB, Créteil, France (N.O.); Department of Public Health, AP-HP, Henri Mondor University Hospital, Créteil, France (N.O.); EA 4391, Université Paris Est Créteil, Créteil, France (A.C., B.B.); Department of Neurology, AP-HP, Henri Mondor University Hospital, Créteil, France (A.C.); Department of Neuroradiology, A. Rothschild Foundation Hospital, Paris, France (A.L.); Paris Cité University, Paris, France (A.L.); Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland (T.K.); Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland (T.K.); Signal Processing Laboratory (LTS 5), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland (T.K.); and Siemens Healthcare SAS, Courbevoie, France (A.M.).
Objectives: Nonenhanced T1-w sequences such as magnetization-prepared 2 rapid acquisition gradient echo (MP2RAGE) and derived fluid and white matter suppression (FLAWS) have demonstrated high performance for detecting brain parenchymal and cervical spine demyelinating lesions in multiple sclerosis. However, their potential for identifying optic nerve (ON) demyelination remains unexplored. The aim of this study was to evaluate the performance of compressed sensing-accelerated (CS) MP2RAGE-FLAWS imaging for detection of ON demyelination lesions compared with T2-w fat-saturated (FS) TSE imaging in a clinical setting.
View Article and Find Full Text PDFVolumetric body composition analysis of the Cancer Genome Atlas reveals novel body composition traits and molecular markers Associated with Renal Carcinoma outcomes.
Sci Rep
November 2024
Mallinckrodt Institute of Radiology, Washington University in St. Louis School of Medicine, Mail Stop Code: 8131, 4559 Scott Ave, St. Louis, MO, 63110, USA.
Clinically, the body mass index remains the most frequently used metric of overall obesity, although it is flawed by its inability to account for different adipose (i.e., visceral, subcutaneous, and inter/intramuscular) compartments, as well as muscle mass.
View Article and Find Full Text PDFAn investigation into the chiropractic practice and communication of routine, repetitive radiographic imaging for the location of postural misalignments.
J Clin Imaging Sci
August 2024
Department of Research, Apollo Spine Rehabilitation, New Jersey, United States.
Many chiropractors use radiological imaging, particularly X-rays, to locate and diagnose the cause of their patients' pain. However, this approach is fundamentally flawed because X-rays provide anatomical information but not functional insights. Pain, tissue damage, and injury do not always correlate directly with X-ray appearances.
View Article and Find Full Text PDFLearning curve analyses in spine surgery: a systematic simulation-based critique of methodologies.
Spine J
October 2024
National Spine Injuries Unit, Mater Misericordiae University Hospital, Dublin, Ireland; University College Dublin School of Medicine, Dublin, Ireland.
Background Context: Various statistical approaches exist to delineate learning curves in spine surgery. Techniques range from dividing cases into intervals for metric comparison, to employing regression and cumulative summation (CUSUM) analyses. However, their inherent inconsistencies and methodological flaws limit their comparability and reliability.
View Article and Find Full Text PDFAn investigation into the chiropractic practice and communication of routine repetitive radiographic imaging for the location of postural misalignments.
J Clin Imaging Sci
June 2024
Department of Research, Apollo Spine, Westville, Indiana, United States.
Many clinicians use radiological imaging in efforts to locate and diagnose the cause of their patient's pain, relying on X-rays as a leading tool in clinical evaluation. This is fundamentally flawed because an X-ray represents a "snapshot" of the structural appearance of the spine and gives no indication of the current function of the spine. The health and well-being of any system, including the spinal motion segments, depend on the inter-relationship between structure and function.
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