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By electron microscopy and image analysis, we find that baculovirus-expressed UL6 is polymorphic, consisting of rings of 11-, 12-, 13-, and 14-fold symmetry. The 12-mer is likely to be the oligomer incorporated into procapsids: at a resolution of 16 A, it has an axial channel, peripheral flanges, and fits snugly into a vacant vertex site. Its architecture resembles those of bacteriophage portal/connector proteins.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525097 | PMC |
| http://dx.doi.org/10.1128/JVI.78.22.12668-12671.2004 | DOI Listing |
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