The aqueous extract of Sphaeranthus senegalensis (Asteraceae) was investigated for anti-diarrhoeal activity in rats. Its effect on castor oil-induced diarrhoea and fluid accumulation and on gastrointestinal (charcoal meal) test was evaluated. Results showed that pre-treatment for 30 min with the extract at 50, 100 and 200 mg/kg, p.o. causes a dose-dependent protection against castor oil-induced diarrhoea and intraluminal fluid accumulation and inhibited gastrointestinal transit motility. These results suggest that the plant contain active constituents that may be useful against diarrhoea.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jep.2004.06.036 | DOI Listing |
Publication Analysis
Top Keywords
sphaeranthus senegalensis
8
castor oil-induced
8
oil-induced diarrhoea
8
fluid accumulation
8
efficacy sphaeranthus
4
senegalensis vaill
4
vaill extract
4
diarrhoea
4
extract diarrhoea
4
diarrhoea rats
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!