Download full-text PDF |
Source |
---|
Eur Stroke J
January 2025
Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy.
Introduction: The efficacy and safety of statins for secondary prevention in patients who have experienced a cardioembolic stroke are not well-defined. However, previous observational data reported hyperlipidemia as a risk factor for both ischemic and bleeding complications in patients with AF and previous stroke. Based on these premises, we conducted a sub-analysis of the RAF and RAF-NOAC studies to evaluate the efficacy and safety of statins in secondary prevention in patients with acute ischemic stroke and AF.
View Article and Find Full Text PDFJ Clin Invest
December 2024
Department of Neurology, UCSF, San Francisco, United States of America.
NMDA receptor mediated autoimmune encephalitis (NMDAR-AE) frequently results in persistent sensory-motor deficits, especially in children, yet the underlying mechanisms remain unclear. This study investigated the long- term effects of exposure to a patient-derived GluN1-specific monoclonal antibody (mAb) during a critical developmental period (from postnatal day 3 to day 12) in mice. We observed long-lasting sensory-motor deficits characteristic of NMDAR-AE, along with permanent changes in callosal axons within the primary somatosensory cortex (S1) in adulthood, including increased terminal branch complexity.
View Article and Find Full Text PDFMedicine (Baltimore)
December 2024
Department of Hepatobiliary Surgery, Yangxin People's Hospital, Yangxin, China.
Rationale: Duplication of gallbladder is a rare anomaly in humans, as it is very rare for a duplication of gallbladder to be missed during the first cholecystectomy and thus require a second cholecystectomy.
Patient Concerns: A 42-year-old man came to our hospital with paroxysmal right upper abdominal pain for 10 days. In addition to the pain, he also had transient jaundice.
Circ Arrhythm Electrophysiol
December 2024
Jessa Ziekenhuis, Hasselt, Belgium (T.P., P.K., N.A., J.V.).
Background: Pulsed field ablation (PFA) is a promising treatment for atrial fibrillation. We report 1-year freedom from atrial arrhythmia outcomes using monopolar PFA delivered through 3 commercial, contact force-sensing focal catheters.
Methods: ECLIPSE AF (NCT04523545) was a prospective, single-arm, multicenter study evaluating acute and chronic safety and performance using the CENTAURI system to deliver focal PFA with TactiCath SE, StablePoint, and ThermoCool ST.
Circ Arrhythm Electrophysiol
December 2024
Electrophysiology Unit, Cardiology Service, Hospital Puerta de Hierro, Madrid, Spain. (V.C.-U., M.S.-D., D.J.-S., C.A.-A., P.V.-M., A.L.-R., D.G.-R., D.S.-O., C.P.-T., E.G.-I., J.T.-R., I.F.-L.).
Background: Superior vena cava (SVC) has been considered a specific trigger in atrial fibrillation development.
Methods: We investigated the efficacy and safety of combining cryoballoon pulmonary vein isolation (PVI) with SVC ablation compared with PVI alone in 100 patients with paroxysmal or non-long-standing persistent atrial fibrillation. Patients were randomly assigned to either the PVI+SVC ablation group or the PVI-only group.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!