Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1177/070674370404900923 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
ATAD3B and SKIL polymorphisms associated with antipsychotic-induced QTc interval change in patients with schizophrenia: a genome-wide association study.
Transl Psychiatry
February 2022
Institute of Mental Health, Peking University Sixth Hospital, Beijing, 100191, China.
QTc interval prolongation is one of the most common antipsychotic-induced side effects which could lead to ventricular tachycardia or Torsade de Pointes, even cardiac arrest. There is very limited understanding on the genetic factors that associated with antipsychotic-induced QTc interval change. We conducted a genome-wide association study (GWAS) of antipsychotic-induced QTc interval change among patients with schizophrenia.
View Article and Find Full Text PDFBazett's correction formula overestimates the corrected QT among patients with antipsychotic induced tachycardia.
Schizophr Res
May 2021
Metro South Addiction and Mental Health Service, Brisbane, Australia; School of Clinical Medicine, University of Queensland, Brisbane, Australia.
EPB41L4A and LEP gene polymorphisms are associated with antipsychotic-induced QTc interval prolongation in Han Chinese.
Psychiatry Res
February 2020
Institute of Mental Health, Tianjin Anding Hospital, Tianjin Medical University, 13 Liulin Rd., Hexi District, Tianjin, 300222, China. Electronic address:
To identify the genetic factors related to antipsychotic-induced QTc interval prolongation (AIQTIP), we analyzed the associations between single nucleotide polymorphisms (SNPs) of candidate genes and quantitative traits of AIQTIP in a Han Chinese population. In total, we collected 112 hospitalized patients suffered from schizophrenia meeting the entry criteria, including 34 first-episode drug-naïve patients (FENP). All patients were treated with a single atypical antipsychotic drug (AAPD) for 4 weeks.
View Article and Find Full Text PDFDiphenhydramine-Refractory Antipsychotic-Induced Dystonia in an Adolescent Male With Cornelia de Lange Syndrome.
J Pediatr Pharmacol Ther
January 2019
Cornelia de Lange Syndrome is a rare genetic disorder that results in distinctive craniofacial deformities, developmental delay, hirsutism, and other physical abnormalities. Case reports suggest some of these patients exhibit sensitivity and paradoxical reactions to certain psychoactive drugs. This report of a 16-year-old male with Cornelia de Lange is the first to describe dystonia from a first-generation antipsychotic that did not respond to conventional treatment with diphenhydramine.
View Article and Find Full Text PDFA molecular pathway analysis informs the genetic risk for arrhythmias during antipsychotic treatment.
Int Clin Psychopharmacol
January 2018
Department of Clinical Medicine, Psychiatric Research Unit West, Aarhus University, Herning, Denmark.
Arrhythmias are a frequent and potentially fatal side effect of antipsychotic treatment. Strict ECG monitoring and clinical interviews are the standards used to prevent arrhythmias. A biologic predictive tool is missing.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!