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Acid-base implications of the Gibbs-Donnan effect during continuous veno-venous hemofiltration.
J Nephrol
March 2025
Department of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy.
Background: This in-vitro and in-vivo study investigates the Gibbs-Donnan effect across the filter during continuous veno-venous hemofiltration (CVVH). In particular, we assessed its acid-base implications, applying the physical-chemical approach.
Methods: A prospective, single-center study was conducted using the PrismaMax machine (Baxter).
Evaluating Continuous Veno-venous Hemodiafiltration Treatment Effects on Biomarkers and Outcomes in Sepsis-Induced Acute Kidney Injury.
Iran J Kidney Dis
February 2025
Department of Nephrology, Baoji People's Hospital, No. 24 Xinhua Lane, Jing'er Road, Weibin District, Baoji 721000, Shaanxi Province, China.
Introduction: Acute kidney injury (AKI) is commonly precipitated by sepsis. Continuous veno-venous hemofiltration (CVVHD) is a critical intervention for managing AKI, but further exploration is needed to understand its effects on novel renal injury markers and patient outcomes. The aim of this study is to evaluate the impact of CVVHD on novel renal injury markers and its prognostic significance in individuals suffering from sepsis-related AKI.
View Article and Find Full Text PDFScientia et Cura: Illuminating the Dark Side of CRRT for Optimal Patient Benefits.
Iran J Kidney Dis
February 2025
Division of Nephrology and Hypertension, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Introduction: Continuous Renal Replacement Therapy (CRRT) is commonly used in patients with hemodynamic instability but is associated with potential complications. Understanding these complications can improve CRRT efficiency and patient outcomes.
Methods: This cross-sectional study investigated CRRT complications in patients > 18 years old who underwent CRRT at a tertiary medical center from 2017 to 2022.
Effects of different hemodialysis modalities combined with low-calcium dialysate on mineral metabolism and vascular calcification in maintenance hemodialysis patients with chronic kidney disease.
J Appl Biomed
December 2024
Southern Medical University, Nanfang Hospital, Department of Organ Transplantation, Guangzhou 510515, Guangdong, China.
Objective: This research investigated the effects of different hemodialysis modalities combined with low-calcium dialysate (LCD) on mineral metabolism and vascular calcification (VC) in maintenance hemodialysis (MHD) patients with chronic kidney disease (CKD).
Methods: General data were collected from 192 cases of MHD patients, who were divided into 4 groups according to the randomized numerical table. Each group was given LCD treatment, and conventional hemodialysis (HD), high-flux HD (HFHD), hemodiafiltration (HDF), and HD + hemoperfusion (HP) were performed, respectively.
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