[Pulmonary infection with Nocardia species: a report of 10 cases].

Nihon Kokyuki Gakkai Zasshi

Department of Chest Medicine, Chiba Aoba Municipal Hospital.

Published: September 2004

AI Article Synopsis

  • The study examined clinical features of pulmonary nocardiosis by reviewing 10 patients from 1998 to 2003.
  • All patients had underlying health issues, with most being immunosuppressed, and 75% of infected patients survived.
  • Quick diagnosis using a gram-stain method improved the survival rate, indicating the need for better diagnostic methods in the future.

Article Abstract

Objective: To investigate the clinical features of pulmonary nocardiosis.

Patients And Methods: We retrospectively reviewed ten consecutive patients (5 men, 5 women; aged 25 to 80 years (average 49.3 years)) with confirmed bacteriological pulmonary nocardiosis from 1998 to 2003. Patients were divided into two groups: infected (8 patients) and isolated (2 patients).

Results: All patients had predisposing factors and/or pulmonary disease. Six were immunosuppressed by steroid therapy with or without other immunosuppressive drugs. The overall survival rate among infected patients was 75.0% (6/8), but the survival rate of patients who were diagnosed speedily by a gram-stain procedure was 85.7% (6/7).

Conclusions: Although pulmonary nocardiosis is difficult to diagnose, prompt use of the gram-staining procedure and appropriate treatment appeared to improve survival. And new diagnostic method is desirable.

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