We report a 27-year-old man with HIV-1 infection who developed acute promyelocytic leukemia (APL) with a novel complex three-way chromosomal translocation t(15;16;17). Induction of remission and consolidation with all-trans-retinoic acid (ATRA)- and anthracycline-based chemotherapy was followed by maintenance therapy consisting of ATRA, 6-mercaptopurine (6-MP), and methotrexate (MTX). Highly active antiretroviral therapy (HAART) was continued with brief interruptions. He remains in complete remission 40 months after diagnosis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/ajh.20192 | DOI Listing |
Publication Analysis
Top Keywords
acute promyelocytic
8
promyelocytic leukemia
8
hiv-1 infection
8
leukemia hiv-1
4
infection case
4
case report
4
report review
4
review literature
4
literature report
4
report 27-year-old
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!