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Relationship between triglyceride levels and different snoring states: a systematic review and meta-analysis.
Eur J Med Res
December 2024
Department of Intensive Care Unit, Affiliated With Inner Mongolia Medical University, Huhehaote, China.
Objective: High triglyceride (TG) levels are important risk factors for cardiovascular disease (CVD). Some recent studies have shown that snoring is also closely related to elevated TG levels. The specific pathogenesis of elevated TG levels in snoring patients is still unclear.
View Article and Find Full Text PDFActive games for increasing social and emotional competencies of young adults in probation system: a one-sample trial study in Izmir city in Turkiye.
BMC Psychol
December 2024
Ege University Institute on Drug Abuse, Toxicology and Pharmaceutical Science, Izmir, Turkey.
Introduction: The prevalence of substance use among young adults has been increasing in Turkiye. Probation as a form of execution continues to grow in popularity around the world, as it has the potential for more successful outcomes than closed institutional execution methods. However, in the face of changing societal and individual needs, the probation system must rapidly adapt to current public realities, especially with new approaches, including the use of purposeful physical movement for young adults who are obliged due to illegal substance use.
View Article and Find Full Text PDFAlarmins and their pivotal role in the pathogenesis of spontaneous abortion: insights for therapeutic intervention.
Eur J Med Res
December 2024
Department of Obstetrics and Gynecology, Reproductive Medicine Center, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, 230022, Anhui, China.
Alarmins are a class of molecules released when affected cells damaged or undergo apoptosis. They contain various chemotactic and immunomodulatory proteins or peptides. These molecules regulate the immune response by interacting with pattern recognition receptors (PRRs) and play important roles in inflammatory response, tissue repair, infection defense, and cancer treatment.
View Article and Find Full Text PDFGenomic Patterns are Associated with Different Sequelae of Patients with Long-Term COVID-19.
Adv Sci (Weinh)
December 2024
State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory of Pathobiology Ministry of Education, China-Japan Union Hospital of Jilin University, Changchun, 130033, China.
In the post-large era, various COVID-19 sequelae are getting more and more attention to health problems. Although the mortality rate of the COVID-19 infection is now declining, it is often accompanied by new clinical sequelae with different symptoms such as fatigue after infection, loss of smell. The degree of age, gender, virus infection seems to be weakly correlated with clinical symptoms.
View Article and Find Full Text PDFAltered chromatin landscape and 3D interactions associated with primary constitutional MLH1 epimutations.
Clin Epigenetics
December 2024
Hereditary Cancer Group, ONCOBELL Program, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Spain.
Background: Lynch syndrome (LS), characterised by an increased risk for cancer, is mainly caused by germline pathogenic variants affecting a mismatch repair gene (MLH1, MSH2, MSH6, PMS2). Occasionally, LS may be caused by constitutional MLH1 epimutation (CME) characterised by soma-wide methylation of one allele of the MLH1 promoter. Most of these are "primary" epimutations, arising de novo without any apparent underlying cis-genetic cause, and are reversible between generations.
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