Ultrasound biomicroscopic analysis of iris profile changes with accommodation in pigmentary glaucoma and relationship to age.

Am J Ophthalmol

Department of Ophthalmology, Ontario Cancer Institute, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada.

Published: October 2004

Purpose: To examine the effect of accommodation on iris profile in pigmentary glaucoma and its relationship to age.

Design: Interventional case series.

Methods: We measured change in iris profile with accommodation in 92 eyes of 92 patients with pigmentary glaucoma.

Results: Mean age was 42 years. Mean change in posterior iris excursion from nonaccommodated to accommodated state was 144.5 microm. (P < .001). Age was plotted against iris excursion with an estimated least-squares regression line. The estimated Pearson correlation coefficient was -0.60, (P < .001). Patients younger than 42 years of age had a mean change in excursion of 209.2 microm compared with 79.8 microm for those patients older than 42 years. (P < .001)

Conclusion: This study found that there is a significant increase in posterior iris bowing in the accommodated state. Increasing age is associated with decreased posterior iris deviation. These findings add evidence to the theory of accommodation-induced reverse pupillary block in pigmentary glaucoma.

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http://dx.doi.org/10.1016/j.ajo.2004.04.048DOI Listing

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