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Should we pay more attention to the potential link between and esophageal cancer in Asian countries.
World J Gastroenterol
December 2024
Department of Gastroenterology, The First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, Anhui Province, China.
The presence of () infection has been indicated to have a protective influence on esophageal cancer (EC) in some studies, but its specific impact on the risk of esophageal squamous cell carcinoma and esophageal adenocarcinoma remains inconclusive. This manuscript comment addresses the recent study by López-Gómez . Despite it was a retrospective observational study without a control group, this study revealed a notably low prevalence of infection among EC patients, indicating a potential association between and EC in Spain.
View Article and Find Full Text PDFRegional action needed to halt antimalarial drug resistance in Africa.
Lancet
December 2024
Mahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok 10400, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK; WorldWide Antimalarial Resistance Network, Oxford, UK. Electronic address:
Economic Burden of Late-Stage Age-Related Macular Degeneration in Bulgaria, Germany, and the US.
JAMA Ophthalmol
December 2024
Retina International, Dublin, Ireland.
Importance: Age-related macular degeneration (AMD) is a highly prevalent and debilitating retinal condition that affects more than 200 million people globally, with the severe late-stage forms-neovascular AMD (nAMD) and geographic atrophy (GA)-affecting more than 11 million people globally. However, much is unknown about the economic burden of the disease.
Objective: To estimate the economic burden associated with late-stage AMD in Bulgaria, Germany, and the US at the societal level.
Curcuma-Based Nutritional Supplements and Risk of Age-Related Macular Degeneration.
JAMA Ophthalmol
December 2024
Department of Ophthalmology, Byers Eye Institute, Horngren Family Vitreoretinal Center, Stanford University School of Medicine, Palo Alto, California.
Importance: Curcuma-based nutritional supplements (CBNS) are natural anti-inflammatory and antioxidant agents that may confer benefits against age-related macular degeneration (AMD).
Objective: To examine the association between the use of CBNS and the risk of development or progression of AMD.
Design, Setting, And Participants: This was a retrospective cohort study with data collection in June of 2024.
Patient-Directed Education to Promote Deprescribing: A Nonrandomized Clinical Trial.
JAMA Intern Med
November 2024
New England Geriatric Research Education and Clinical Center, VA Boston Health Care System, Jamaica Plain, Massachusetts.
Article Synopsis
- The study investigates how patient-directed educational materials can help clinicians reduce unnecessary prescriptions for specific medication groups, notably proton pump inhibitors and high-risk diabetes treatments.
- Conducted across three VA medical centers, the trial involved 5071 patients and compared an intervention cohort receiving educational brochures to a control group from the previous year.
- Results showed a higher deprescribing rate among the intervention group (29.5%) compared to the control group (25.8%), indicating that the educational intervention positively affected medication management practices.
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