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Post-exercise neural plasticity is augmented by adding blood flow restriction during low work rate arm cycling.
Exp Physiol
January 2025
Centre for Healthy Ageing, Health Futures Institute, Murdoch University, Perth, Australia.
Blood flow restriction (BFR) combined with low work rate exercise can enhance muscular and cardiovascular fitness. However, whether neural mechanisms mediate these enhancements remains unknown. This study examined changes in corticospinal excitability and motor cortical inhibition following arm cycle ergometry with and without BFR.
View Article and Find Full Text PDFCosmetic surgery among women - a cross-sectional study.
Tidsskr Nor Laegeforen
January 2025
Institutt for psykologi, Oslo Nye Høyskole.
Background: Studies from 2003 and 2008 indicated that 7-8 % of adult women in Norway had undergone cosmetic surgery. As there is little research available on the current situation, the main purpose of this study was to map the use of, desire for and social acceptance of cosmetic surgery. We also wanted to identify differences in demographic and psychosocial factors between women who have undergone cosmetic surgery, those who desire such surgery and those who do not.
View Article and Find Full Text PDFThe role of CXCL12/CXCR4/CXCR7 axis in cognitive impairment associated with neurodegenerative diseases.
Brain Behav Immun Health
February 2025
Pediatric and Urology and Regenerative Medicine Research Center, Gene, Cell and Tissue Research Institute, Children Medical Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Neurodegenerative diseases, including Alzheimer's Disease (AD), Parkinson's Disease (PD), Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS), are characterized by progressive neuronal loss and cognitive impairment (CI). The: Cysteine-X-cysteine chemokine ligand 12(CXCL12)/CXC chemokine receptor type 4 (CXCR4)/CXC chemokine receptor type 7 (CXCR7) axis has emerged as a critical molecular pathway in the development of CI in these disorders. This review explores the role of this axis in the pathogenesis of CI across these neurodegenerative diseases, synthesizing current evidence and its implications for targeted therapies.
View Article and Find Full Text PDFEmerging Delivery Systems for Enabling Precision Nucleic Acid Therapeutics.
ACS Nano
January 2025
Beijing Key Laboratory for Bioengineering and Sensing Technology, Daxing Research Institute, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China.
Nucleic acid therapeutics represent a highly promising treatment approach in modern medicine, treating diseases at the genetic level. However, these therapeutics face numerous challenges in practical applications, particularly regarding their stability, effectiveness, cellular uptake efficiency, and limitations in delivering them specifically to target tissues. To overcome these obstacles, researchers have developed various innovative delivery systems, including viral vectors, lipid nanoparticles, polymer nanoparticles, inorganic nanoparticles, protein carriers, exosomes, antibody oligonucleotide conjugates, and DNA nanostructure-based delivery systems.
View Article and Find Full Text PDFComparison of Different Hemostatic Net Applications on Rat Dorsal Skin Flap Model.
Aesthet Surg J
January 2025
Department of Histology and Embryology, Gazi University, Ankara, Türkiye.
Background: There are several articles discussing the use of a hemostatic net to close dead spaces, but no in-vivo experimental studies have simultaneously examined the histology and tissue perfusion of these techniques.
Objectives: Our aim is to compare variations of the hemostatic net technique commonly used in current practice.
Methods: Two different hemostatic net suturing techniques and two times of suture removal were tested, with a control group for comparison.
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