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Novel Lipid Formulation Increases Absorption of Oral Cannabidiol (CBD).
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Department of Psychiatry, Oxford University, Warneford Hospital, Oxford OX3 7JX, UK.
: Cannabidiol (CBD) is an approved treatment for childhood epilepsies and a candidate treatment for several other CNS disorders. However, it has poor oral bioavailability. We investigated the effect of a novel lipid formulation on its absorption in humans and on its tissue distribution in mice.
View Article and Find Full Text PDFMass Spectrometric Based Metabolomics of the Saudi Cultivar of Fenugreek ( L.): A Combined GC-MS, Antimicrobial and Computational Approach.
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December 2024
Department of Biology, College of Science, Qassim University, Buraydah 51452, Saudi Arabia.
In Saudi Arabia, numerous plant species with promising medicinal properties are cultivated, widely traded, and commonly utilized in traditional medicine, including fenugreek (). This study aimed to comprehensively assess the phytochemical composition and antimicrobial potential of the Saudi cultivar of fenugreek using an integrative approach combining in vitro and in silico methodologies. A comprehensive investigation was conducted on the ethanol extract of fenugreek seeds, assessing its antibacterial, antifungal, properties.
View Article and Find Full Text PDFUse of Chemical and Colorimetric Changes to Age Frass for Termite Management.
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Forest Research Institute, University of the Sunshine Coast, Sippy Downs 4556, Australia.
Drywood termites are problematic timber pests worldwide. , the West Indian drywood termite, is among the most important of these pests, in part due to its cryptic nature, making it hard to detect in structures and thereby easy to transport. Primary detections are commonly made by the observation of frass deposits evacuated through kick-holes, often leading to fumigation of the building to effectively eradicate the pest.
View Article and Find Full Text PDFPhenolic Content and Anti-Inflammatory Activity of Cultivated and Wild-Type Extracts in Murine Bone Marrow-Derived Macrophages.
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Latvian Institute of Organic Synthesis, 21 Aizkraukles Str., LV-1006 Riga, Latvia.
, commonly known as sweet woodruff, is a perennial herbaceous plant that contains coumarin and is recognized for its medicinal properties. In this study, the influence of sunlight exposure on the phytochemical composition and anti-inflammatory potential of extracts is assessed. The extracts from cultivated and wild-grown plants were analyzed via chromatographic and mass spectrometric methods.
View Article and Find Full Text PDFCitrus aurantium 'Changshan-huyou' physiological premature fruit drop: A promising prebiotic to tackle obesity.
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Hunan Agriculture Product Processing Institute; Dongting Laboratory; Hunan Academy of Agricultural Sciences, Changsha, Hunan Province 410125, China. Electronic address:
Background: Presently, the mitigation and governance of obesity have surfaced as significant public health dilemmas on a global scale. A wealth of studies indicated that the host gut microbiota is instrumental in regulating the interplay between high-fat diet (HFD) intake and the pathogenesis of obesity. Physiological premature fruit drop, a major byproduct of citrus, is rich in a variety of bioactive constituents, yet its potential has remained underutilized for an extended period.
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