Complex carbohydrates are an essential part of a healthy diet. However, many people suffer from varying degrees of carbohydrate intolerance, resulting in embarrassing gastrointestinal symptoms and avoidance of these components of a healthy diet. To facilitate awareness and discussion, we propose the phrase "complex carbohydrate intolerance" (CCI) as a broad term to encompass the range of symptoms associated with carbohydrate intolerance. While various treatments offer symptomatic relief, enzyme replacement therapy targets the cause of the problem: an enzyme deficiency. The enzyme, alpha-galactosidase, currently only found in the over-the-counter product, Beano, may be an effective preventative treatment for CCI.
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BMJ Paediatr Open
December 2024
Pediatric Department, University of Antioquia, Medellin, Colombia.
Background: Post-transplantation diabetes mellitus and carbohydrate intolerance (PTDM/iCHO) are complications following solid organ transplantation, which significantly increases the risk of graft loss and mortality. However, data concerning long-term outcomes in paediatric kidney transplant recipients with PTDM/iCHO are scarce. This study aimed to evaluate the risk of graft loss in paediatric kidney transplant recipients with PTDM or iCHO compared with non-PTDM/iCHO.
View Article and Find Full Text PDFCongenital diarrhea and enteropathies (CoDEs) condition is a rare cause of chronic diarrhea in infants that can be challenging to diagnose. This article discusses key signs to recognize in considering a CoDEs diagnosis and provides an overview of the diagnostic process. We report a late preterm twin infant with intractable watery diarrhea starting shortly after birth.
View Article and Find Full Text PDFJ Ayurveda Integr Med
December 2024
Sri Dharmasthala Manjunatheshwara College of Ayurveda & Hospital, Kuthpady, Udupi, India.
Background: Gestational Diabetes Mellitus (GDM) is a metabolic condition that develops in course of pregnancy. The World Health Organization describes it as carbohydrate intolerance that causes hyperglycemia of varying severity and manifests itself or is first noticed during pregnancy. Early prediction is now possible, owing to the application of cutting-edge methods like machine learning.
View Article and Find Full Text PDFNutrients
August 2024
Joint Research Unit on Endocrinology, Nutrition and Clinical Dietetics, Health Research Institute La Fe, 46026 Valencia, Spain.
The rise in food intolerances and celiac disease, along with advanced diagnostic techniques, has prompted health professionals to seek effective and economical testing methods. This study evaluates combining genetic tests with routine carbohydrate-absorption breath tests to classify patients with chronic gastrointestinal disorders into therapeutic groups, enhancing dietary management and improving gut health and quality of life. Forty-nine patients with suspected carbohydrate intolerance underwent genetic testing for lactase non-persistence, hereditary fructose intolerance, and celiac disease risk.
View Article and Find Full Text PDFWest Afr J Med
May 2024
Department of Medicine, Aminu Kano University Teaching Hospital, Kano.
Background: Prediabetes is an important risk factor for the development of type 2 diabetes and is common in Nigeria. Prediabetes often progresses to type 2 diabetes but effective intervention can reverse the carbohydrate intolerance associated with the condition. No studies have been reported among Nigerians on the natural outcome or effect of intervention in prediabetes.
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